What is NAD?

Learn how NAD+ can extend your healthspan.

Are We Supposed to Live Past 40?

Seragon’s Aging Intervention Drug SRN-901 Achieves One of the Largest Extensions of Lifespan and Healthspan to Date

Does Melatonin Improve Cognition?

Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins

Approved Drugs that Increase the Chances of Living a Longer Life

Can We Slow Down Aging? Inside the Cutting-Edge Science of Peptides, Stem Cells, and NAD+

New Mayo Clinic Research Finds Aged Skin Cells Cause Cognitive Decline

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

Clinical Trials

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

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Aging & Longevity

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Based primarily on discussions with guests on his popular podcast, the supplements Joe Rogan has taken include NMN, resveratrol, vitamin D, fish oil, and more.

Based primarily on discussions with guests on his popular podcast, the supplements Joe Rogan has taken include NMN, resveratrol, vitamin D, fish oil, and more.

NAD+ declines with age and with metabolic disorders like obesity, so young and healthy individuals may not benefit from NAD+ boosting supplements.

NAD+ declines with age and with metabolic disorders like obesity, so young and healthy individuals may not benefit from NAD+ boosting supplements.

Aging & Longevity

94-Year-Old Clint Eastwood’s Longevity Secrets

A series of realizations and personal experiences — like his father’s death from cardiovascular disease — have propelled Clint Eastwood to take care of his health for graceful aging.

Aging & Longevity

Stanford scientist Andrew Huberman, Ph.D., gives his thoughts on why he takes grapeseed extract (high in resveratrol), NMN, and NR, while also mentioning the downsides of NAD+ drip therapy.

Stanford scientist Andrew Huberman, Ph.D., gives his thoughts on why he takes grapeseed extract (high in resveratrol), NMN, and NR, while also mentioning the downsides of NAD+ drip therapy.

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Latest News

Diabetes & Obesity

Scientists cure type 2 diabetes by replicating the function of the pancreas with stem cells.

Scientists cure type 2 diabetes by replicating the function of the pancreas with stem cells.

Aging & Longevity

Want to Get Fit? Look at What Sylvester Stallone Does at 78

Sylvester Stallone’s daily diet includes egg whites as well as broiled chicken and fish for plenty of protein, and his most current workouts focus on the chest, back, abs, and legs for optimal longevity.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Scientists say combining exercise with NAD+ (nicotinamide adenine dinucleotide) precursors may synergistically improve physical performance.

Scientists say combining exercise with NAD+ (nicotinamide adenine dinucleotide) precursors may synergistically improve physical performance.

Aging & Longevity

How 84-Year-Old Acting Legend Chuck Norris Defies Aging

Chuck Norris eats whole, nutrient-dense foods, maintains a rigorous workout routine that includes martial arts training, and practices meditation to stay young.

Aging & Longevity

What if You Could Optimize Aging? Andrew Huberman Says These Methods Might Just Do That

Dr. Andrew Huberman highlights the potential of NAD+ and BPC-157 for aging while stressing the importance of practicing healthy daily habits.

Aging & Longevity

Anti-aging enthusiast and multimillionaire Bryan Johnson warns against high uric acid levels and offers guidance on how to keep them low to slow aging.

Anti-aging enthusiast and multimillionaire Bryan Johnson warns against high uric acid levels and offers guidance on how to keep them low to slow aging.

Aging & Longevity

Brad Stanfield, MD, explains the pros and cons of supplementing with omega-3s, psyllium husk, and creatine.

Brad Stanfield, MD, explains the pros and cons of supplementing with omega-3s, psyllium husk, and creatine.

Is Your Gut Microbiome Failing? Gary Brecka and Dr. Will Bulsiewicz Talk Gut Health and Disease

Gary Brecka and Dr. Will Bulsiewicz discuss how gut health, fueled by fiber and a healthy microbiome, plays a vital role in reducing inflammation and preventing age-related diseases.

Brain & Neurons

Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys.

Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys.

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