What is NAD?

The cutoff for vitamin B12 deficiency is too low, according to new findings showing that “normal” B12 levels are associated with neurological deficits in older adults.

In a first proof of principle human trial, researchers demonstrated that plasma proteins from young donors lower inflammatory markers in elderly people who underwent surgery.

The prescription drug rapamycin a.k.a. sirolimus, an FDA-approved mTOR inhibitor, increases the brain volume of cognitively normal individuals at risk for developing Alzheimer’s disease.

Dr. Aseem Malhotra, a cardiologist from the UK, says pharmaceutical company-sponsored research distorts the scientific evidence behind the effectiveness of cholesterol-lowering statins against heart disease.

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases.

Carvedilol, a blood pressure medication, and the senolytic agent ABT-263 both attenuate cellular senescence—an age-related, dysfunctional cellular state—driven by a gut bacterial metabolite in mice.

Creatine improves vascular health while lowering blood glucose and triglyceride levels in older adults.

Ergothioneine — a naturally occurring compound found in mushrooms — increases the muscle size of middle-aged rats while extending the lifespan of worms.

Researchers project dementia cases in the U.S. to double by 2060, revealing higher incidence in women, Black adults, and APOE ε4 carriers