What is NAD?

Learn how NAD+ can extend your healthspan.

New Study Shows Increasing COX7RP Improves Energy Production and Extends Lifespan

Seragon’s Aging Intervention Drug SRN-901 Achieves One of the Largest Extensions of Lifespan and Healthspan to Date

How to Boost Mitochondrial Density and Quality for Longevity

New Study: Vitamin B9 Combats Cell Senescence to Slow Vascular Aging

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

Dark Chocolate Compound Linked to Slower Aging, Study Finds

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

NMN & NR

Nicotinamide mononucleotide (NMN) increases blood levels of nicotinamide adenine dinucleotide (NAD+) to alleviate age-related disorders like metabolic disease and cardiovascular dysfunction.

Clinical Trials

New Study Shows NMN Substantially Increases NAD+ and Enhances Physical Performance

NMN increases blood NAD+, enhances walking distance over a six-minute period, and improves a self-assessed evaluation of health, especially at higher doses in healthy adults.

Harvard Study: NMN Cuts Weight, Cholesterol, and Blood Pressure in Overweight Adults

NMN supplementation significantly reduces body weight, cholesterol, and blood pressure when blood fills the heart (diastolic blood pressure) in overweight or obese adults.

Latest UPenn Study Reveals NMN and NR Have Similar Efficacy in a Kidney Disease Model

Supplementing with nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) confers comparable benefits against kidney disease in male mice.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

Most Popular

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults.

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL.

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL.

Aging & Longevity

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation.

Aging & Longevity

Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

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Latest News

Aging & Longevity

The Rise of China’s Longevity Movement: A Quest to Defy Aging

China’s national project to crush aging encompasses longevity labs, “immortality islands,” and grapeseed pills, as well as exorbitant claims based on sometimes questionable science.

Aging & Longevity

Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes

On 60 Minutes, Peter Attia reveals how performance, prevention, and emotional resilience contribute to aging well.

A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death.

A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death.

Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.

Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.

Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations.

Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations.

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice.

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice.

Aging & Longevity

Johns Hopkins Research Review: Parkinson’s Drug Extends Multiple Species' Lifespan

L-deprenyl, a drug used to treat Parkinson’s disease and major depressive disorder, has been shown to modestly extend lifespan across species, from mice to rats to hamsters.

Aging & Longevity

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

In a randomized human trial, combining nicotinamide with vitamin B6 increases stem cell activation and muscle-growth capacity in response to exercise.

In a randomized human trial, combining nicotinamide with vitamin B6 increases stem cell activation and muscle-growth capacity in response to exercise.

Brain & Neurons

The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide riboside chloride (NRC) counteracts neuronal damage caused by alcohol consumption in mice.

The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide riboside chloride (NRC) counteracts neuronal damage caused by alcohol consumption in mice.

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