<p>Participants: Healthy older adults </p>
<p>Dosage: 1 mg/day of rapamycin for 8 weeks </p>


Older adults taking low-dose rapamycin exhibit a reduction in senescent cells — cells that contribute to age-related diseases and a shorter lifespan. 

Associate professor at Oxford University and corresponding author on the study, Lynne S Cox, MA, PhD (image: researchgate.com).

Immunity

The plant-based compound Harmine counteracts the cellular aging triggered by sleep deprivation in animal models and human cells.

Study conducted at the Leibniz Institute on Aging. 

Aging &amp; Longevity

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

An aging research aficionado, Dr. Josh Helman, shares five supplements that can help fight the effects of aging: nitric oxide, NMN, honokiol, modified citrus pectin, and creatine.

(Harvard-trained aging expert, Dr. Josh Helman | Jupiter Medical Center)

Harvard-trained aging expert Dr. Josh Helman unveils his top five supplements to fight against aging.

Seragon Biosciences has launched its new sleep and longevity optimizer, Enlivien, featuring technology based on a Harvard University collaboration. 


Eric Verdin, M.D., and Peter Attia, M.D., discuss the controversy surrounding NAD+ (nicotinamide adenine dinucleotide), the best method for replenishing NAD+, and more.


99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Despite his previous battles with alcoholism, Dick Van Dyke is approaching his 10th decade of life and serves as a beacon for preserving physical function into his golden years.

(At age 99, Dick Van Dyke still maintains a remarkable degree of physical function | NBC News)

At age 99, Dick Van Dyke avoids harmful foods, eats foods high in antioxidants, and keeps moving, a regimen that may have contributed to his astounding longevity.

In a randomized clinical trial, active and healthy older adults who took a multi-supplement and omega-3 fatty acids saw a reduction in age-related chronic inflammation after 12 weeks. 

Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

A combined treatment of NMN with 78c (a small molecule that inhibits an NAD+-degrading enzyme) enhances the effects of the anti-cancer CAR-T cell therapy in aged mice and human cells.

(A CAR-T cell [red] attacking a cancer cell [blue] | Crown Bioscience Blog)

Cancer

The theory says our brain allocates resources to energy-consuming senescent cells at the body’s expense, accounting for gray hair, muscle shrinkage, and other signs of aging.

Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

(Dr. David Sinclair believes an age-reversing pill is under development | YouTube)

Harvard’s Dr. David Sinclair believes an age-reversing pill may become available within a decade and that researchers may find a way to one day double human lifespan.

New Oxford Study: Powerful Longevity Drug Rapamycin Targets Cell Senescence

Scientist May Have Discovered a New Drug that Makes Up for Lost Sleep

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

Enlivien: A New Dawn for Sleep and Longevity

Top Aging Expert & Peter Attia Discuss NAD+ Precursors: Taking NMN and NR Together

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Clinical Omega-3 Longevity Stack: A New Clue in the Fight Against Age-Related Chronic Inflammation

Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

Are Senescent Cells Turning Your Hair Gray? A New Aging Theory

Anti-Aging Breakthrough? Harvard’s David Sinclair Predicts Age-Reversing Pill by 2035