The Rise of China’s Longevity Movement: A Quest to Defy Aging

China’s national project to crush aging encompasses longevity labs, “immortality islands,” and grapeseed pills, as well as exorbitant claims based on sometimes questionable science.

(Attendees at a conference in Shanghai try out a cryogenic chamber in which temperatures plummeted to approximately -200 degrees Fahrenheit, meant to slow aging | New York Times)

A surge in the Chinese public’s interest in longevity science has led to substantial investments from the state and private companies in aging research.

Aging &amp; Longevity

Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes 

On 60 Minutes, Peter Attia reveals how performance, prevention, and emotional resilience contribute to aging well. 

<p data-start="153" data-end="243"><strong data-start="153" data-end="163">Model:</strong> Male ApoE−/− mice fed a high-fat diet for 12 weeks to induce atherosclerosis.</p>
<p data-start="153" data-end="243"><strong data-start="246" data-end="257">Dosage:</strong> Methyl-β-cyclodextrin (Mß-CD) at <strong data-start="291" data-end="341">2.0 g/kg, subcutaneous injection, twice a week</strong></p>


 A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death. 

Cardiovascular

<p>Participants: Healthy middle-aged to older adults (average age: ~53 years) </p>
<p>Dosage: 1,000 mg/day of urolithin A for 28 days </p>


Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations. 

Columbia University in New York City (image: Columbia.edu). 

<p>Model: 24-month-old male C57BL/6J mice </p>
<p>Dosage: 1% w/v of betaine for three weeks </p>


The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Johns Hopkins Research Review: Parkinson’s Drug Extends Multiple Species' Lifespan

L-deprenyl, a drug used to treat Parkinson’s disease and major depressive disorder, has been shown to modestly extend lifespan across species, from mice to rats to hamsters.

L-deprenyl, a drug prescribed to treat Parkinson’s disease and major depressive disorder, has been shown to modestly extend average lifespan across mammalian model organism species.

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<p data-start="97" data-end="197">Model: Aged mice (18 months old, C57BL/6 strain) and aged rhesus macaques (18–21 years old).</p>
<p data-start="97" data-end="197">Dosage: Mice received 100 µg of EVs^ABPC via tail vein injection twice per week for 4 weeks.<br data-start="297" data-end="300" data-is-only-node="" />Rhesus macaques received 200 µg/kg of EVs^ABPC intravenously once per week for 20 weeks.</p>
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Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

<p>Participants: Healthy male adults between the ages of 18 and 50 </p>
<p>Dosage: 714 mg/day of nicotinamide and 19 mg/day of pyridoxine for nine days </p>


In a randomized human trial, combining nicotinamide with vitamin B6 increases stem cell activation and muscle-growth capacity in response to exercise. 

Skin &amp; Muscle

<p>Model: Male C57BL/6 mice given continuous alcohol for 4 weeks </p>
<p>Dosage: 350 mg/kg/day of nicotinamide riboside chloride for 2 weeks </p>


The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide riboside chloride (NRC) counteracts neuronal damage caused by alcohol consumption in mice. 

The Rise of China’s Longevity Movement: A Quest to Defy Aging

Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes

Scientists Find a New Way to Stop Dangerous Artery Plaques From Growing

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

The Inflammation Myth: New Insights on Aging

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Johns Hopkins Research Review: Parkinson’s Drug Shown to Extend Lifespan Across Mammalian Species

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

NAD+ Booster and Vitamin B6 Activate Stem Cells to Counter Muscle Shrinkage, New Studies Show

NAD+ Supplement Counters Alcohol-Induced Brain Aging, According to New Study