Stanford’s Dr. Andrew Huberman Reveals His Supplement Protocol for Optimizing Health and Performance 

Stanford scientist Dr. Andrew Huberman shares his blueprint for developing a supplementation routine to optimize health and performance. 



Dr. Andrew Huberman (Photograph courtesy of Mike Blabac; Collage: Gabe Conte)

Explore Dr. Huberman's methods for health and optimization through strategic supplementation and behavioral protocols. 

Aging &amp; Longevity

With inspiration from scientists and physicians like Dr. Andrew Huberman and Dr. Peter Attia, Cavaliere expounds on the five exercises you can start today to potentially live longer. 

Athlean X’s Jeff Cavaliere (athleanx.com)

Participants: Overweight women aged 64 ± 18
Dosage: 20 g of olive oil (mostly monounsaturated fat) in place of margarine in the morning

Certain Fats for Breakfast Reduce Inflammation

Older women who ate olive oil or margarine with breakfast had fewer circulating inflammatory molecules than those who ate butter, suggesting which fat is better for cardiovascular aging. 


Immunity

Unlocking the Secrets of Agelessness: Jared Leto's Strategies for Timeless Youthfulness

Despite his youthful appearance, Hollywood heartthrob and musician Jared Leto is actually 51 years old and maintains his ageless looks by avoiding alcohol and cigarettes, exercising, and eating a healthy diet.

Hollywood celebrity and musician Jared Leto is 51 years old but maintains a seemingly ageless appearance by avoiding alcohol and cigarettes, getting plenty of sleep and exercise, and eating a healthy diet.

Model: Male mice deficient in the apolipoprotein E (ApoE) gene fed a high-cholesterol diet to model atherosclerosis 
Dose (oral): 400 mg/kg/day of nicotinamide riboside (NR)

Nicotinamide riboside (NR) reduces cholesterol, artery plaque buildup, and inflammation in a mouse model for atherosclerosis — artery plaque buildup.

Research conducted at the Chinese University of Hong Kong (image: facts.net). 

Cardiovascular

Model: Male Swiss albino mice
Dosage: 100 mg/kg per day for 18 months

New Study: Green Tea Molecule Extends Lifespan and Alleviates Fat Tissue Senescence

Epigallocatechin gallate (EGCG) supplementation substantially prolongs lifespan and suppresses senescence — an age-related, dysfunctional cellular state — in the fat tissue of mice.

(An aged mouse drinking green tea with an EGCG molecule on the left | NAD.com)

EGCG supplementation over 18 months increases median lifespan by ~25% and significantly lowers fat tissue senescence in mice.

Bryan Johnson: When Too Much Exercise Stops Slowing Aging 

When millionaire Bryan Johnson is asked why he doesn’t exercise more for longevity, he explains that there is such a thing as too much exercise. 


Bryan Johnson preparing to do some heavy leg presses. 

Combined senolytics dasatinib and quercetin (D+Q) — compounds that remove age-driving cells — rejuvenate the proliferation of sperm stem cells. 


Aged mice have fewer sperm cells than young mice, similar to humans. 

Others

Model: HET3 mice, which are genetically heterogenous to model the diversity of human genetics more precisely than other lab mice, which are usually genetically homogenous 
Dosage: 67% reduction in dietary intake of isoleucine

Limiting dietary intake of the amino acid — protein building block — isoleucine significantly extends the lifespan of male mice and modestly extends the lifespan of female mice. 


Harvard Scientist David Sinclair's Techniques for Reducing His Biological Age by a Decade

Despite being 54 years old, Sinclair says his health is better than a 20-year-old, and he maintains a reduced biological age — a measurement indicating slowed aging — by exercising and managing what and when he eats.

(David Sinclair | Business Today YouTube segment)

Harvard’s David Sinclair has a biological age a whole decade younger than his age in years, and his routine includes exercising three times per week, eating less often, and avoiding certain foods.

Stanford’s Dr. Andrew Huberman Reveals His Supplement Protocol for Optimizing Health and Performance

5 Exercises to Live Longer: Elite Strength Coach Jeff Cavaliere from Athlean-X

Olive Oil and Margarine Beat Butter in Breakfast Battle for Reducing Inflammation: Spanish Study

Unlocking the Secrets of Agelessness: Jared Leto’s Strategies for Timeless Youthfulness

Study Shows NAD+ Precursor NR Combats Cardiovascular Disease by Unclogging Arteries

New Study Reveals Green Tea Molecule Extends Lifespan and Alleviates Fat Tissue Senescence

Living Longevity Experiment Bryan Johnson: Is it Possible to Exercise Too Much?

Senolytics Enhance Male Reproductive Potential by Rejuvenating Sperm Stem Cells: Japan Study

Study Shows Avoiding Consumption of Protein Building Block Isoleucine Increases Lifespan

Harvard Scientist David Sinclair’s Techniques for Reducing His Biological Age by a Decade