This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

womanwithcancerduringchemotherapyrecoveringfromillnessinhospital

Woman,With,Cancer,During,Chemotherapy,Recovering,From,Illness,In,Hospital

Supplementing with NMN protects the heart against chemotherapy-induced heart complications that include disrupted tissue organization and blood pumping abilities.

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

According to French scientists, no organ system appears as vulnerable to aging as the cardiovascular system, and anti-aging therapeutics may help mitigate the effects of cardiovascular disease.

kroemer

Kroemer

(The principal investigator behind the review, aging researcher Guido Kroemer | Olympiad in Cardiovascular Medicine)

Anti-aging therapeutics may prevent and slow age-related cardiovascular dysfunction.

Cardiovascular

Participants: Healthy males (age range: 70-76)
Dosage: 1 mg/kg/day of rapamycin for 8 weeks

Supplementing with rapamycin leads to improvements in cardiac and vascular function in older men, suggesting this longevity-associated drug may counteract cardiovascular aging. 

musi

Musi

Nicolas Musi, MD, professor of medicine and an author of the study (image: sanantoniomag.com). 

α-Lipoic Acid: Efficacy, Safety, and Dosage

α-lipoic acid is an antioxidant naturally produced by the body, which is also available as a supplement, and human trials indicate that it has neuroprotective and male fertility-enhancing effects.

alpha-lipoic-acid

alpha-lipoic acid

(α-lipoic acid’s molecular structure | Neuroneeds)

α-lipoic acid is a potent antioxidant, which human trials suggest has neuroprotective and male fertility-enhancing properties.

Metabolism

Model: 39 adults between 18 and 30 years old and 36 adults between 65 and 80 years old
Dosage: ∼595 mg NO3− twice daily from two 70 mL shots of nitrate-rich beetroot juice

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

A new human trial yields data showing that nitrate-rich beetroot juice alters the oral microbe composition and lowers blood pressure in older participants.

exeter-1-1-1-1

University of Exeter

A new human trial provides evidence that nitrate-rich beetroot juice beneficially modifies the oral microbe composition and lowers blood pressure in older individuals.

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

An aging research aficionado, Dr. Josh Helman, shares five supplements that can help fight the effects of aging: nitric oxide, NMN, honokiol, modified citrus pectin, and creatine.

josh-helman

Josh Helman

(Harvard-trained aging expert, Dr. Josh Helman | Jupiter Medical Center)

Harvard-trained aging expert Dr. Josh Helman unveils his top five supplements to fight against aging.

Aging &amp; Longevity

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults. 

ultrasound

Ultrasound

An ultrasound of the carotid artery with arrows pointing to plaques (image: avicennacardiology.com). 

Model: 8 adults with peripheral artery disease 
Dosage: 1,000 mg of NR daily for four weeks

New Study Suggests NR Modestly Improves Cognition in Age-Related Vascular Disease

Taking NR was associated with improved blood flow to a specific brain region following cognitive stimulation, as well as trends toward enhanced cognition in patients with age-related vascular disease.

andriy

Andriy

(The study’s principal investigator, Andriy Yabluchanskiy | LinkedIn)

Taking NR is associated with improved blood perfusion to a brain region involved in memory and daily task organization, as well as a trend toward enhanced cognition.

Brain &amp; Neurons

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

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Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Model: 24-month-old male and female C57BL/6J mice
Dosage: 3 mg/kg/day, delivered continuously over 8 weeks

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals

Scientists show that elamipretide restores muscle and heart function in aging mice but doesn’t affect epigenetic or transcriptomic age.


old-lady-on-bike

old lady on bike

Activist Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins

Dr. Aseem Malhotra, a cardiologist from the UK, says pharmaceutical company-sponsored research distorts the scientific evidence behind the effectiveness of cholesterol-lowering statins against heart disease.

aseemmalhotra

AseemMalhotra

(Dr. Aseem Malhotra, cardiologist | The Telegraph)

Rodent Study Shows NMN Protects the Heart from Chemotherapy Toxicity

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

Longevity Drug Rapamycin Improves the Heart of Older Adults, New Study Shows

An Overview of α-Lipoic Acid: Efficacy, Safety, and Dosage

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

New Study Reveals: High-Dose Supplement Shrinks Arterial Plaque by 36%

New Study Suggests NR Modestly Improves Cognition in Human Subjects

Longevity Prescription

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals

Activist Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins