This NAD+ precursor shields the heart from injury caused by a chemotherapeutic in rats, preventing the disruption of tissue organization and blood pumping abilities.

womanwithcancerduringchemotherapyrecoveringfromillnessinhospital

Woman,With,Cancer,During,Chemotherapy,Recovering,From,Illness,In,Hospital

Supplementing with NMN protects the heart against chemotherapy-induced heart complications that include disrupted tissue organization and blood pumping abilities.

Model: Male C57BL/6 J 
Dosage: 5 mM spermidine in drinking water

Supplementing aged and young mice with spermidine increases muscle blood vessel growth and blood flow, implying improved cardiovascular health and exercise performance. 


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Koji Ikeda

Corresponding investigator Koji Ikeda, M.D., Ph.D. | Research Gate 

Cardiovascular

Model: 6-month-old C57BL/6J mice up to 18-months-old (12-month intervention)
Dosage: 7.3% (of total grams of food) alpha linolenic acid (ALA) in food

Lesser-Known Omega-3 Protects Against Cardiovascular Aging

Plant-based omega-3 fatty acid — alpha-linolenic acid (ALA) — prevents heart dysfunction, reduces cardiac scarring, and improves artery elasticity in aged mice. 

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Principal Investigator Dr. Jürg H. Beer | Badener Tagblatt 

Does Pursuing a Superhero Physique through Steroid Use Accelerate Aging? 

Research in the past few decades suggests a strong association between impaired cardiac health and long-term use of anabolic steroids. 


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Handsome,Man,With,Big,Muscles,,Posing,At,The,Camera,In

Model: Male mice
Dose: Intravenous injection of 100 µL of cold-temperature-exposed exosomes

Cold Exposure Reduces Blood Vessel Hardening while Deterring Senescence

Exposing mice to cold reduces artery calcium buildup and releases vesicles that reduce senescent cells — cells that promote aging.  

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Cross-section of arteries from mice exposed to room temperature (left) or cold temperature (right) with calcification stained in red.

Unlocking the Power of Cold: Surprising New Study Shows How Chilling Out Can Benefit Your Vascular Health

Model: Male rats
Dosage: Doxorubicin (DOX) for 12 days (2 mg/kg/day)

Heart Health Improved by Gold Particles That Boost NAD+, Study Shows  

Apigenin-coated gold particles protect rat hearts from damage by blocking cell death.

goldnanoparticles3dillustration-biotechnologicalandscientificbackground

Gold,Nanoparticles,,3d,Illustration.,Biotechnological,And,Scientific,Background

Scientists use stem cell therapy to improve heart function and reduce the risk of stroke and heart attack in heart failure patients.

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Perin

Lead investigator, Emerson C. Perin, M.D., Ph.D. | The Texas Heart Institute 

Scientists show that injecting a heart disease mouse model with NAD+ improves heart function and reduces cardiac damage. 


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Principal Investigator Dr. Paul Delgado-Olguín | The Hospital for Sick Children 

Model: Sprague-Dawley rats
Dosage: 20 mg/kg NAD+ by intravenous injection

Rats given intravenous NAD+ following a heart attack have improved survival, better heart function, and fewer neurological deficits.

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main

Senior author, Dr. Wanchun Tang | Exostat Medical 

Model: Male LDLR-/- mice
Dosage: 1 mg/mL in N-acetylcysteine drinking water

Potent Antioxidant Reduces Artery Cholesterol Buildup

Long-term supplementation with the antioxidant N-acetylcysteine (NAC) prevents blood vessel cholesterol accumulation in aged mice with high cholesterol.


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Liu800x450

Senior author, Dr. Zhenguo Liu | University of Missouri 

Model: female C57BL/6J mice
Dosage: 5 mg/kg Dasatinib and 50 mg/kg Quercetin intraperitoneally injected 3x per week for 4 weeks

Senolytics Promote Cardiac Regeneration in Heart Attack Model 

Italian scientists show that the senolytics Dasatinib plus Quercetin (D + Q) improve heart function and restores cardiac regenerative capacity in aged mice following myocardial infarction (heart attack). 

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Corresponding author, Dr. Daniele Torrella and team | Fame Di Sud  

Rodent Study Shows NMN Protects the Heart from Chemotherapy Toxicity

Latest Study Shows Spermidine Significantly Boosts Blood Flow & Promotes Cardiovascular Health

Swiss Study Uncovers Benefits of Lesser-Known Omega-3 in Protecting Against Heart and Artery Deterioration

Does Pursuing a Superhero Physique through Steroid Use Accelerate Aging?

Chilling News for Vascular Aging: Cold Exposure Reduces Blood Vessel Hardening while Deterring Senescence

Heart Health Improved by Gold Particles That Boost NAD+, Study Shows

Stem Cell Therapy Improves Heart Function and Reduces Risk of Stroke and Heart Attack: Largest Human Trial of its Kind

Canadian Study Suggests NAD+ Could Help Prevent Heart Failure

Study Shows NAD+ Protects Heart and Brain From Heart Attack

Study Shows Potent Antioxidant Reduces Artery Cholesterol Buildup

Italian Study Shows Senolytics Promote Cardiac Regeneration After Heart Attack