A natural supplement, quercetin, targets age-promoting senescent cells, reduces inflammation, and counteracts blood vessel aging in men with heart disease. 

Study conducted at the University of Montreal in Quebec, Canada (image: ledevoir.com) 

Clinical Trials

<p>Model: 27-month-old male C57BL/6N mice </p>
<p>Dosage: 50 mg/kg/day of fisetin for 1 week, followed by no treatment for 2 weeks, followed by another week of treatment  </p>


Plant-based molecule fisetin preserves muscle mass and strength in older mice via senolytic action — removal of senescent (dysfunctional) cells.


Study conducted at the University of Colorado Boulder (image: govtech.com) 

Skin &amp; Muscle

Seragon’s RESTORIN and the Evolution of Aging Interventions Containing NAD+ Precursors

Aging interventions that include NAD+ precursors have evolved, adding components targeting various hallmarks of aging, from inflammation to cell waste elimination.

Some aging intervention products with NAD+ precursors, like Seragon’s Restorin, have evolved to include additional components targeting multiple hallmarks of aging.

Aging &amp; Longevity

Abdominal fat is associated with a dramatic increase in the risk of early death in generally healthy older adults who are not obese. 

(Image: AARP / AHMET YARALI / GETTY IMAGES)

Metabolism

Will Interventions that Delay Aging in Animals Work for Humans?

Researchers have shown that using certain agents targeting hallmarks of aging (like inflammation) can extend lifespan in mice, yet human trials are just beginning to uncover whether they work in humans.

(Aged individuals may benefit from aging interventions that work in animal models | NAD.com)

Search Result: senolytic supplementation

A Natural Senolytic Supplement Curbs Heart Aging in New Clinical Trial

Fisetin Fights Frailty: New Study Shows Supplment Preserves Strength

Seragon’s RESTORIN and the Evolution of Aging Interventions Containing NAD+ Precursors

New Research Study Claims Belly Fat Increases Risk of Early Death by Whopping 365%

Will Interventions that Delay Aging in Animals Work for Humans?