Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes 

On 60 Minutes, Peter Attia reveals how performance, prevention, and emotional resilience contribute to aging well. 

Aging &amp; Longevity

<p>Participants: Healthy middle-aged to older adults (average age: ~53 years) </p>
<p>Dosage: 1,000 mg/day of urolithin A for 28 days </p>


Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

<p>Model: 24-month-old male C57BL/6J mice </p>
<p>Dosage: 1% w/v of betaine for three weeks </p>


The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

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<p data-start="97" data-end="197">Model: Aged mice (18 months old, C57BL/6 strain) and aged rhesus macaques (18–21 years old).</p>
<p data-start="97" data-end="197">Dosage: Mice received 100 µg of EVs^ABPC via tail vein injection twice per week for 4 weeks.<br data-start="297" data-end="300" data-is-only-node="" />Rhesus macaques received 200 µg/kg of EVs^ABPC intravenously once per week for 20 weeks.</p>
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Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

<p>Participants: Healthy male adults between the ages of 18 and 50 </p>
<p>Dosage: 714 mg/day of nicotinamide and 19 mg/day of pyridoxine for nine days </p>


In a randomized human trial, combining nicotinamide with vitamin B6 increases stem cell activation and muscle-growth capacity in response to exercise. 

Search Result: muscle aging

Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

NAD+ Booster and Vitamin B6 Activate Stem Cells to Counter Muscle Shrinkage, New Studies Show