Participants: Prefrail older adults
Dosage: 50 mg/day of losartan for at least 8 weeks

Losartan, a common blood pressure medication, increases the survival rate of mice and improves the metabolic outlook of pre-frail older adults. 

Principal Investigator of the study, Dr. Peter M. Abadir (image: jhu.edu).

Aging &amp; Longevity

Joe Rogan’s Top Supplements for 2026

Joe Rogan’s latest supplement stack includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

(Joe Rogan on set for his podcast | Spotify Newsroom)

Joe Rogan’s updated supplement stack for 2026 includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

Model: Male 16-month-old C57BL/6 mice 
Dosage: Intraperitoneal injection of 20 mg/kg/day of inosine for 4 weeks

Inosine Supplment Combats New Driver of Aging 

Scientists discover that inosine—a type of molecule called a purine nucleoside—alleviates multiple-organ aging in mice, and restores the oxygen delivery capacity of red blood cells. 


An artistic depiction of red blood cells delivering oxygen to surrounding tissues. 

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

A naturally occurring compound, α-lipoic acid, helped elderly mice think like younger mice by restoring energy balance and calming brain inflammation, according to Second Hospital of Hebei Medical University researchers.

(Alpha-lipoic acid’s molecular structure | Sasha’s of Saratoga)

Brain &amp; Neurons

Model: 14- to 15-month-old male C57BL/6J mice
Dosage: 50 mg injection of 3′-deoxyadenosine (cordycepin) because it was shown not to be absorbed if administered orally

Mushroom Compound Prolongs Lifespan If Taken At Correct Time

In mice, cordycepin—a molecule found in cordyceps mushrooms—prolongs lifespan and improves memory, strength, cardiac function, hormone levels, and metabolism. 


Cordyceps mushrooms (image: antioxi-supplements.com). 

Search Result: Weight Gain

New Johns Hopkins Study: FDA-Approved Losartan May Extend Lifespan

Joe Rogan’s Top Supplements for 2026

Inosine Supplment Counters New Driver of Aging

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

Cordyceps Mushroom Molecule Prolongs Lifespan If Taken At Correct Time of Day, New Study Shows