Model: Male Sprague Dawley rats
Dosage: 1.5 mg/kg body or rapamycin injected 3 times a week for 4 weeks

The longevity-associated drug rapamycin diminishes muscle size and strength in young rats when compared to untreated but calorically restricted young rats. 

Skin &amp; Muscle

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

The longevity biotech company, MetaShape, has a new compound designed to restore cellular nicotinamide adenine dinucleotide (NAD+) and offset elevated cholesterol, cognitive decline, and neurodegeneration.

Supplementing with ergothioneine — a compound found in lion’s mane mushrooms — enhances the verbal memory of elderly individuals. 

(Image: marthastewart.com) Lion’s mane mushrooms.

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s

Recent research from Zhejiang University School of Medicine in Hangzhou, China, demonstrates that administering NAD+ precursors to mice can safeguard the brain against neurodegeneration

(Zhejiang University School of Medicine | Panda Admission)

Brain &amp; Neurons

Model: C57BL/6J mice
Dosage: 500 mg/kg/day of Urolithin A in food

Supplementing with urolithin A prevents age-related hearing loss and mitochondrial dysfunction in mice. 

Search Result: Neurodegeneration

Over-Supplementing in Youth Can Harm Long-Term Health, Says New Research

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

Ergothioneine Longevity Supplement Enhances Verbal Memory

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s

Urolithin A Anti-Aging Supplement Prevents Hearing Loss, New Research Shows