<p>Model: Apoe−/− C57BL/6J mice fed a high-fat diet</p>
<p>Dosage: 1 × 109 CFU per 0.1 mL of Bacteroides uniformis administered to mice via oral gavage for 12 weeks and 25 mg/kg of pentadecanoic acid via oral gavage three times per week for eight weeks</p>


New Study: Gut Bacteria Metabolite Reduces Arterial Plaque Burden by 50%

Researchers identified pentadecanoic acid, a gut-bacteria-produced metabolite, that lowered LDL cholesterol and limited arterial plaque buildup in mice.

(A depiction of various gut bacteria in the intestines | NAD.com)

A gut bacterial metabolite reduced arterial plaque buildup by about 50% in mice, revealing a potential link between gut microbes and cholesterol regulation.

Cardiovascular

The Future of Longevity: Could Humans Really Live to 150?

A TIME Magazine longevity panel, featuring Harvard’s David Sinclair, explores whether breakthroughs in AI, cellular rejuvenation, and research on sex differences could help today’s children live far longer.

(An image illustrating the possibility of some humans achieving a 150-year lifespan in the future | NAD.com)

David Sinclair and Jennifer Garrison discuss whether AI advancements, cellular rejuvenation techniques, and research on sex differences can make a 150-year lifespan possible.

Aging &amp; Longevity

Scientists find that meloxicam preserves muscle mass and strength in aged mice while sustaining mitochondrial function and activating multiple molecules associated with longevity. 


Skin &amp; Muscle

In the largest study of its kind, Viennese scientists analyzed over 25, 000 human tissue slices with AI to determine the architectural changes that occur with aging and how to predict disease. 


By examining chemical tags on DNA that modulate our genes, scientists have discovered which genes are most affected by aging across more than a dozen human tissues.

The study was led by Dr. Nir Eynon from the Australian Regenerative Medicine Institute (image: vu.edu.au). 

Search Result: Nature Medicine

New Study: Gut Bacteria Metabolite Reduces Arterial Plaque Burden by 50%

The Future of Longevity: Could Humans Really Live to 150?

Repurposed Arthritis Drug Counters Muscle Mass Loss with Age, New Study Shows

Researchers Pull the Strings of Artificial Intelligence to Measure Aging: New Study

NAD+: One of Few Correctable Networks During Aging, New Study Shows