The Rise of China’s Longevity Movement: A Quest to Defy Aging

China’s national project to crush aging encompasses longevity labs, “immortality islands,” and grapeseed pills, as well as exorbitant claims based on sometimes questionable science.

(Attendees at a conference in Shanghai try out a cryogenic chamber in which temperatures plummeted to approximately -200 degrees Fahrenheit, meant to slow aging | New York Times)

A surge in the Chinese public’s interest in longevity science has led to substantial investments from the state and private companies in aging research.

Aging &amp; Longevity

Model: Male ApoE−/− mice fed a high-fat diet for 12 weeks to induce atherosclerosis.
Dosage: Methyl-β-cyclodextrin (Mß-CD) at 2.0 g/kg, subcutaneous injection, twice a week

 A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death. 

Cardiovascular

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose

A new computer simulation suggests aging occurs when cells and tissues lose their developmental goals, offering a fresh perspective on rejuvenation strategies.

(The article’s principal investigator, Michael Levin | Tufts Now)

An innovative computer model simulates aging, suggesting that cells and tissues lose their developmental goals, leading to physiological deterioration.

Model: UM-HET3 Mice 
Dosage: 0, 75, 150, 300, 600, and 1200 ng epicatechin/mg food; 0, 0.075, 0.15, 0.3, 0.6, and 1.2 ng halofuginone/mg food; and 0, 37.5, 75, 150, 300, and 600 ng mitoglitazone/mg food, all given ad libitum in food starting at seven months old

Three Compounds Show Promise for Male Longevity

Data from a rigorous longevity study show promise for three new compounds, adding to the repertoire of mouse lifespan-extending substances.

(The three compounds’ effects on median lifespan extension | Rapamycin Longevity News)

The world’s most rigorous longevity study presents data showing promise for three new lifespan-extending compounds in male mice.

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity. 


Search Result: Nature Medicine

The Rise of China’s Longevity Movement: A Quest to Defy Aging

Scientists Find a New Way to Stop Dangerous Artery Plaques From Growing

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose

Three Compounds Show Promise for Male Longevity

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging