Model: 39 adults between 18 and 30 years old and 36 adults between 65 and 80 years old
Dosage: ∼595 mg NO3− twice daily from two 70 mL shots of nitrate-rich beetroot juice

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

A new human trial yields data showing that nitrate-rich beetroot juice alters the oral microbe composition and lowers blood pressure in older participants.

A new human trial provides evidence that nitrate-rich beetroot juice beneficially modifies the oral microbe composition and lowers blood pressure in older individuals.

Cardiovascular

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Despite his previous battles with alcoholism, Dick Van Dyke is approaching his 10th decade of life and serves as a beacon for preserving physical function into his golden years.

(At age 99, Dick Van Dyke still maintains a remarkable degree of physical function | NBC News)

At age 99, Dick Van Dyke avoids harmful foods, eats foods high in antioxidants, and keeps moving, a regimen that may have contributed to his astounding longevity.

Aging &amp; Longevity

Model: Cybrids composed of Rho0 cells with human platelet mitochondrial DNA from participants between 7 days old and 99 years old 
Dosage: 5 mM of n-Acetyl-L-Cysteine and 3 mM of nicotinamide riboside, with medium changed every three days until the cell population reached between 1 and 10 million

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

(Telomeres [highlighted in gold] at the ends of a chromosome | NAD.com)

A new study suggests the NAD+ precursor NR combined with the antioxidant NAC may counteract telomere shortening, a hallmark of aging.

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


Search Result: NAC

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

New Study: Combining NR with NAC May Slow Telomere Shortening

Longevity Prescription

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol