Based on current scientific evidence, Dutch researchers have ranked existing anti-aging interventions based on how likely they are to protect against DNA damage and aging. 


On the far right, one of the researchers, Dr. Jan H.J. Hoeijmakers (image: amazinggerasmusmc.nl). 

DNA Repair

Model: Female New Zealand white rabbits 
Dosage: 20 mg/kg of fisetin

Fisetin reduces susceptibility to a heart condition called atrial fibrillation (AF) and eliminates age-promoting senescent cells in aged rabbits.  

On the right is Principal Investigator Gideon Koren, MD (image: brownhealth.org).

Cardiovascular

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

Bryan Johnson debates 20 skeptics on anti-aging in Jubilee’s viral episode and challenges assumptions about lifespan, science, and the future of human health.


Aging &amp; Longevity

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

Fayoum University researchers found that cranberry polyphenols improve metabolic markers, cognition, and oxidative stress to the same degree as the drug metformin.

A new study suggests cranberry extract has effects against aging that rival metformin.

Participants: Adults over the age of 60
Dosage: 3,750 mg of niacin twice daily (after gradual dose increase), 150 mg of dihydroberberine twice daily, 50 mg of taxifolin (with 500 mg of vitamin C and 15 mg of zinc) twice daily, 50 mg of tocotrienols twice daily

A combination of supplements, including the NAD+ precursor nicotinic acid, improves cholesterol, allowing some participants to cease taking statins.  

Study conducted by Professor Emeritus Joseph Keenan, MD, at the University of Minnesota. 

Search Result: Mortality

NAD+ Ranked #2 Most Powerful Way to Reverse DNA Damage & Aging

Natural Compound Fisetin Combats Heart Disease by Eliminating Senescent Cells: New Brown University Study

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

NAD+ Boosting Supplement Challenges Cholesterol-Lowering Statins in Anti-Aging Research