The Disregarded Organ That Could Hold the Key to Fighting Aging

Scientists are researching ways to regrow the thymus, an immune organ that vanishes with age, to suppress the tolls of aging.

(The thymus [colored orange] is located in the upper chest | NAD.com)

An organ involved in immunity, the thymus, vanishes as people get older, and scientists are researching ways to regrow it to fight aging.

Immunity

Longevity Medicine’s Peptides Craze: Evidence, Delivery Challenges, and Expert Opinions

Advocates say peptides offer significant benefits against aging, while researchers warn that these claims outpace the evidence.

(Peptides are often injected with a syringe | Harvard Health)

Proponents say peptides offer significant effects against aging, while skeptical scientists say these claims outpace the evidence.

Aging &amp; Longevity

Model: Skin, arterial, and lens tissue from donors between the ages of 20 and 25 and also 75 
Dosage: 5 µM solution of CMLase, incubated overnight

Bioengineered Enzyme Shows Ability to Reverse Molecular Aging in Human Tissue

An engineered enzyme reverses age-related protein damage that researchers have long thought irreversible in human eye, skin, and artery tissues.

(A bioengineered enzyme [purple structure] cleaves a prevalent type of AGE [brown glob] on protein residues that are part of protein filaments [dull green chains] | The Scientist)

A bioengineered enzyme reverses age-related protein damage, long thought of as irreversible damage, in human lens, skin, and artery tissues.

Basic Research

Model: SAMP8 mice 
Dosage: ~25 mg/kg/day of PQQ or PQI administered in food

Supplementing with the antioxidant pyrroloquinoline quinone (PQQ) modestly extends the lifespan of age-accelerated mice while improving their strength.  


Model: Six adults who received intravenous NAD+ and eight adults who received intravenous NR
Dosage: 500 mg of intravenous NAD+ or 500 mg of intravenous NR daily for four consecutive days

Pilot Human Study Supports Safety of NAD+ IV and NR IV Infusions

A Stanford study supports the short-term safety of NAD+ and NR infusion therapies, and participants who received NR infusions exhibited significantly lower HbA1c (a blood test that reflects average blood sugar over two to three months).

(An IV bag containing a solution with NAD+ | Crete Fertility Centre)

A Stanford human trial provides the first data supporting the safety of NAD+ IV and NR IV therapies.

Search Result: Liver King

The Overlooked Organ That Could Hold the Key to Fighting Aging

Longevity Medicine’s Peptides Craze: Evidence, Delivery Challenges, and Expert Opinions

New Research: Bioengineered Enzyme Shows Ability to Reverse Molecular Aging in Human Tissue

Powerful Antioxidant PQQ Extends Life and Improves Strength, New Study Shows

Pilot Human Study Supports Safety of NAD+ IV and NR IV Infusions