University of California (UC) Berkeley scientists moderately extend the lifespan of old mice by giving them oxytocin and a compound that inhibits inflammation.  

Aging &amp; Longevity

Model: UM-HET3 Mice 
Dosage: 0, 75, 150, 300, 600, and 1200 ng epicatechin/mg food; 0, 0.075, 0.15, 0.3, 0.6, and 1.2 ng halofuginone/mg food; and 0, 37.5, 75, 150, 300, and 600 ng mitoglitazone/mg food, all given ad libitum in food starting at seven months old

Three Compounds Show Promise for Male Longevity

Data from a rigorous longevity study show promise for three new compounds, adding to the repertoire of mouse lifespan-extending substances.

(The three compounds’ effects on median lifespan extension | Rapamycin Longevity News)

The world’s most rigorous longevity study presents data showing promise for three new lifespan-extending compounds in male mice.

Researchers Identify Key Cellular Changes Around Age 50 That Accelerate Aging

The Chinese Academy of Sciences' findings may explain why aging makes us sicker and suggest new ways to detect and reverse aging.

(Chinese Academy of Sciences | Ferdowsi University of Mashhad)

Model: 39 adults between 18 and 30 years old and 36 adults between 65 and 80 years old
Dosage: ∼595 mg NO3− twice daily from two 70 mL shots of nitrate-rich beetroot juice

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

A new human trial yields data showing that nitrate-rich beetroot juice alters the oral microbe composition and lowers blood pressure in older participants.

A new human trial provides evidence that nitrate-rich beetroot juice beneficially modifies the oral microbe composition and lowers blood pressure in older individuals.

Cardiovascular

Model: Primary hippocampal neurons from non-transgenic C57BL/6 (nTg) and triple-transgenic 3xTg-AD mice; age groups: young (2–6 mo), middle (8–11 mo), and old (17–28 mo).
Dosage: Nicotinamide 2 mM + EGCG 2 µM applied to cultured neurons for 16 h (in vitro).

Study shows that brief nicotinamide + EGCG treatment restores neuronal energy in 16–24 hours, restores autophagy, reduces amyloid-beta buildup, and boosts neuron survival by ~22% in aging/Alzheimer’s lab models.

Search Result: EPA

New UC Berkeley Study: Oxytocin and Anti-Inflammatory Combo Prolongs Life

Three Compounds Show Promise for Male Longevity

Researchers Identify Key Cellular Changes Around Age 50 That Accelerate Aging

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

Nicotinamide + Ergothioneine Reboot Autophagy and Ease Hallmarks of Brain Aging