The Disregarded Organ That Could Hold the Key to Fighting Aging

Scientists are researching ways to regrow the thymus, an immune organ that vanishes with age, to suppress the tolls of aging.

(The thymus [colored orange] is located in the upper chest | NAD.com)

An organ involved in immunity, the thymus, vanishes as people get older, and scientists are researching ways to regrow it to fight aging.

Immunity

Longevity Medicine’s Peptides Craze: Evidence, Delivery Challenges, and Expert Opinions

Advocates say peptides offer significant benefits against aging, while researchers warn that these claims outpace the evidence.

(Peptides are often injected with a syringe | Harvard Health)

Proponents say peptides offer significant effects against aging, while skeptical scientists say these claims outpace the evidence.

Aging &amp; Longevity

How to Slow Aging: 7 Tips from a Danish Aging Expert

Danish aging expert Morten Scheibye-Knudsen shares seven ways to slow aging, including taking NR (nicotinamide riboside) and the diabetes medication metformin.

(Professor Morten Scheibye-Knudsen | BBC Science Focus)

Danish aging expert Morten Scheibye-Knudsen does things like taking NR and metformin to slow his biological aging

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<p class="PDq2pG_selectionAnchorContainer" data-start="0" data-end="125">Model: 4-week-old <span class="hover:entity-accent entity-underline inline cursor-pointer align-baseline"><span class="whitespace-normal">SM/J</span></span> mice (with <span class="hover:entity-accent entity-underline inline cursor-pointer align-baseline"><span class="whitespace-normal">C57BL/6J</span></span> comparison mice)</p>
<p data-start="127" data-end="279" data-is-last-node="" data-is-only-node="">Dosage: Weekly intraperitoneal injections of 40 mg/kg Navitoclax or 5 mg/kg Dasatinib + 50 mg/kg Quercetin from 4 to 6–8 or 17 weeks of age.</p>
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Dasatinib and Quercetin Delay Early-Onset Disc Degeneration in Mice

Researchers find that clearing senescent cells preserves disc structure and slows early-onset disc degeneration in mice.


<p><span style="font-weight: 400;">Model: 5xFAD mouse model for Alzheimer’s disease </span></p>
<p><span style="font-weight: 400;">Dosage: Oral administration of 457 mg/kg/day of glucosamine for 2 weeks </span></p>


Supplementing with glucosamine, a compound found in our cartilage, increases the risk of mortality from dementia in certain individuals while also worsening memory in mice that model dementia. 

Study led by Dr. Ramon Sun on the far right (image: mbi.ufl.edu). 

Search Result: Clinical Trials

The Disregarded Organ That Could Hold the Key to Fighting Aging

Longevity Medicine’s Peptides Craze: Evidence, Delivery Challenges, and Expert Opinions

How to Slow Aging: 7 Tips from a Danish Aging Expert

Dasatinib and Quercetin Delay Early-Onset Disc Degeneration in Mice

Common Joint Health Supplement May Progress Dementia, New Study Finds