Does NAD+ (nicotinamide adenine dinucleotide) really help with aging? A team of international scientists reviews the latest and ongoing clinical trials.

Part of the research team, including Dr. Evandro Fei Fang (middle), from the University of Oslo and Akershus University Hospital in Norway (image: med.uio.no). 

<p>Model: C57BL/6J mice, J20 mice, and 3xTg mice<br />
Dosage: 4.3 μEq l−1 of lithium in drinking water starting at 10 to 12 months of age and continued for 10 to 14 months during aging </p>


Harvard Study: A Low Dose of Lithium May Preserve Cognitive Resilience with Age

Researchers uncover significantly lower brain lithium levels in Alzheimer’s disease patients, and supplementing with a low-dose lithium salt restores memory in an Alzheimer’s disease mouse model.

(The study’s principal investigator, Bruce Yankner [center], with four laboratory employees | The Boston Globe)

A Harvard study suggests lower levels of lithium in the brains of patients with Alzheimer’s disease and that lithium supplementation may help preserve cognitive resilience.

Brain &amp; Neurons

In a randomized clinical trial, active and healthy older adults who took a multi-supplement and omega-3 fatty acids saw a reduction in age-related chronic inflammation after 12 weeks. 

Immunity

Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

(Dr. David Sinclair believes an age-reversing pill is under development | YouTube)

Harvard’s Dr. David Sinclair believes an age-reversing pill may become available within a decade and that researchers may find a way to one day double human lifespan.

Aging &amp; Longevity

A vaccine targeting an enzyme that breaks down NAD+, called CD38, counteracts signs of aging in mice. 


Search Result: Clinical Trials

NAD+ and Aging: What the Latest Research Says

Harvard Study: A Low Dose of Lithium May Preserve Cognitive Resilience with Age

Clinical Omega-3 Longevity Stack: A New Clue in the Fight Against Age-Related Chronic Inflammation

Anti-Aging Breakthrough? Harvard’s David Sinclair Predicts Age-Reversing Pill by 2035

Anti-Aging Vaccine Boosts Strength, Memory & NAD+ in New Study