Model: Male 16-month-old C57BL/6 mice 
Dosage: Intraperitoneal injection of 20 mg/kg/day of inosine for 4 weeks

Inosine Supplment Combats New Driver of Aging 

Scientists discover that inosine—a type of molecule called a purine nucleoside—alleviates multiple-organ aging in mice, and restores the oxygen delivery capacity of red blood cells. 


An artistic depiction of red blood cells delivering oxygen to surrounding tissues. 

Aging &amp; Longevity

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

A naturally occurring compound, α-lipoic acid, helped elderly mice think like younger mice by restoring energy balance and calming brain inflammation, according to Second Hospital of Hebei Medical University researchers.

(Alpha-lipoic acid’s molecular structure | Sasha’s of Saratoga)

Brain &amp; Neurons

Model: 14- to 15-month-old male C57BL/6J mice
Dosage: 50 mg injection of 3′-deoxyadenosine (cordycepin) because it was shown not to be absorbed if administered orally

Mushroom Compound Prolongs Lifespan If Taken At Correct Time

In mice, cordycepin—a molecule found in cordyceps mushrooms—prolongs lifespan and improves memory, strength, cardiac function, hormone levels, and metabolism. 


Cordyceps mushrooms (image: antioxi-supplements.com). 

Could Aging Leave a "Memory" That Spreads and Even Passes to the Next Generation?

A new aging model posits that aging imprints signatures across molecular, tissue, and organ system levels, and these signatures may also transmit across generations.

(A new theory posits that imprinted cellular signatures of aging can transmit between generations | NAD.com)

A new theory posits that aging imprints molecular-, cellular-, tissue-, and organ system-level signatures that may transmit across generations.

Participants: Healthy overweight adults between the ages of 45 and 55 
Dosage: 3 grams/day of ginseng for 28 days

Ginseng Boosts NAD+ and Telomeres: New Study in Middle-Aged Adults

Ginseng supplementation boosts NAD+ (nicotinamide adenine dinucleotide) and lengthens telomeres in middle-aged adults, suggesting an amelioration of aging. 


Panax ginseng Meyer (image: farmaimpresa.com).

Search Result: China

Inosine Supplment Counters New Driver of Aging

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

Cordyceps Mushroom Molecule Prolongs Lifespan If Taken At Correct Time of Day, New Study Shows

Could Aging Leave a “Memory” That Spreads and Even Passes to the Next Generation?

Ginseng Boosts NAD+ and Telomeres: New Study in Middle-Aged Adults