The Overlooked Organ That Could Hold the Key to Fighting Aging

Scientists are researching ways to regrow the thymus, an immune organ that vanishes with age, to suppress the tolls of aging.

(The thymus [colored orange] is located in the upper chest | NAD.com)

An organ involved in immunity, the thymus, vanishes as people get older, and scientists are researching ways to regrow it to fight aging.

Immunity

<div class="qMYqUG_convSearchResultHighlightRoot">
<div class="" data-turn-id-container="request-WEB:358025a4-babd-4cd5-8368-0989249581f5-4" data-is-intersecting="true">
<section class="text-token-text-primary w-full focus:outline-none has-data-writing-block:pointer-events-none [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto R6Vx5W_threadScrollVars scroll-mb-[calc(var(--scroll-root-safe-area-inset-bottom,0px)+var(--thread-response-height))] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]" dir="auto" data-turn-id="request-WEB:358025a4-babd-4cd5-8368-0989249581f5-4" data-turn-id-container="request-WEB:358025a4-babd-4cd5-8368-0989249581f5-4" data-testid="conversation-turn-10" data-turn="assistant">
<div class="text-base my-auto mx-auto pb-10 [--thread-content-margin:var(--thread-content-margin-xs,calc(var(--spacing)*4))] @w-sm/main:[--thread-content-margin:var(--thread-content-margin-sm,calc(var(--spacing)*6))] @w-lg/main:[--thread-content-margin:var(--thread-content-margin-lg,calc(var(--spacing)*16))] px-(--thread-content-margin)">
<div class="[--thread-content-max-width:40rem] @w-lg/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn" data-conversation-screenshot-content="">
<div class="flex max-w-full flex-col gap-4 grow">
<div class="min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal outline-none keyboard-focused:focus-ring [.text-message+&amp;]:mt-1" dir="auto" tabindex="0" data-message-author-role="assistant" data-message-id="b889d53a-36fb-4739-ae44-5127c67b0f7b" data-message-model-slug="gpt-5-5" data-turn-start-message="true">
<div class="flex w-full flex-col gap-1 empty:hidden">
<div class="markdown prose dark:prose-invert wrap-break-word w-full light markdown-new-styling">
<p class="PDq2pG_selectionAnchorContainer" data-start="0" data-end="125">Model: 4-week-old <span class="hover:entity-accent entity-underline inline cursor-pointer align-baseline"><span class="whitespace-normal">SM/J</span></span> mice (with <span class="hover:entity-accent entity-underline inline cursor-pointer align-baseline"><span class="whitespace-normal">C57BL/6J</span></span> comparison mice)</p>
<p data-start="127" data-end="279" data-is-last-node="" data-is-only-node="">Dosage: Weekly intraperitoneal injections of 40 mg/kg Navitoclax or 5 mg/kg Dasatinib + 50 mg/kg Quercetin from 4 to 6–8 or 17 weeks of age.</p>
</div>
</div>
</div>
</div>
<div class="z-0 flex min-h-[46px] justify-start"></div>
<div class="mt-3 w-full empty:hidden">
<div class="text-center"></div>
</div>
</div>
</div>
</section>
</div>
</div>
<div class="pointer-events-none -mt-px h-px translate-y-[calc(var(--scroll-root-safe-area-inset-bottom)-14*var(--spacing))]" aria-hidden="true"></div>


Dasatinib and Quercetin Delay Early-Onset Disc Degeneration in Mice

Researchers find that clearing senescent cells preserves disc structure and slows early-onset disc degeneration in mice.


Aging &amp; Longevity

<p>Model: Six adults who received intravenous NAD+ and eight adults who received intravenous NR</p>
<p>Dosage: 500 mg of intravenous NAD+ or 500 mg of intravenous NR daily for four consecutive days</p>


Pilot Human Study Supports Safety of NAD+ IV and NR IV Infusions

A Stanford study supports the short-term safety of NAD+ and NR infusion therapies, and participants who received NR infusions exhibited significantly lower HbA1c (a blood test that reflects average blood sugar over two to three months).

(An IV bag containing a solution with NAD+ | Crete Fertility Centre)

A Stanford human trial provides the first data supporting the safety of NAD+ IV and NR IV therapies.

Russia’s $27 Billion Bet on Beating Aging—Hype or Hope?

With an ambitious goal of conquering aging, Russia is investing $26 to $28 billion in a national health initiative.

(Russian leader, Vladimir Putin | RBC-Ukraine)

Cellular reprogramming, an innovative age-reversal technology, stimulates the regeneration of heart cells after a heart attack in mice. 

Search Result: CAR T Therapy

The Overlooked Organ That Could Hold the Key to Fighting Aging

Dasatinib and Quercetin Delay Early-Onset Disc Degeneration in Mice

Pilot Human Study Supports Safety of NAD+ IV and NR IV Infusions

Russia’s $27 Billion Bet on Beating Aging—Hype or Hope?

New Age-Reversing Tech Helps Heart Regenerate, Scientists Find