While improving immune health, the NAD+ (nicotinamide adenine dinucleotide) precursor NR (nicotinamide riboside) may induce anxiety-like behavior in stressed, aged mice. 


The study was funded by the National Institute on Aging, one of the National Institutes of Health (NIH). 

Immunity

A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults. 

An ultrasound of the carotid artery with arrows pointing to plaques (image: avicennacardiology.com). 

Cardiovascular

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity. 


Brain &amp; Neurons

A 167-study analysis reveals that rapamycin prolongs lifespan as effectively as dietary restriction: reducing food intake without entering a state of malnourishment.

Aging &amp; Longevity

<p>Model: UM-HET3 mice and 5XFAD mice<br />
Dosage: UM=HET3 mice received 180 mg/kg canagliflozin in chow starting at seven months of age, and FXFAD mice received 180 mg/kg canagliflozin in chow beginning at three months of age</p>


New Study: Diabetes Medication Improves Cognition and Alleviates Alzheimer’s Progression

The diabetes drug canagliflozin improves learning and memory in middle-aged male mice and reduces brain plaques in Alzheimer’s model mice.

The FDA-approved diabetes medication canagliflozin improves cognition in a mouse model of Alzheimer’s disease in males only.

Search Result: Animal study

Anti-Aging NAD+ Precursor Supplement May Promote Anxiety, New Study Shows

New Study Reveals: High-Dose Supplement Shrinks Arterial Plaque by 36%

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging

Anti-Aging Drug Rapamycin Extends Life as Much as Dieting, New Study Shows

Diabetes Medication Improves Cognition and Alleviates Alzheimer’s Progression, Suggests New Study