A new U.S. Army study shows that waist circumference and belly fat are far stronger determinants of circulating testosterone levels than aging.


An image from a previous publication authored by Dr. Karl E. Friedl, one of the U.S. Army scientists on the current study. 

Aging &amp; Longevity

Model: Male COX7RP transgenic mice with systemic overexpression of COX7RP, aged under standard laboratory conditions and compared with age-matched wild-type controls.
Dosage: Not applicable. COX7RP activity was increased via genetic overexpression rather than drug administration.

Boosting mitochondrial efficiency by increasing COX7RP activity extended lifespan in mice while improving energy production and reducing inflammation.

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

Fayoum University researchers found that cranberry polyphenols improve metabolic markers, cognition, and oxidative stress to the same degree as the drug metformin.

A new study suggests cranberry extract has effects against aging that rival metformin.

Model: Two-month-old male C57BL/6J mice fed a high-fat diet to induce obesity 
Dosage: 400 mg/kg/day of NR for eight weeks

Scientists find that NR (nicotinamide riboside) supplementation preserves brown fat tissue in mice, reducing their body weight and maintaining the health of their mitochondria. 

An artist’s rendering of a brown fat cell (image: Alioui Ma/shutterstock.com). 

Diabetes &amp; Obesity

Participants: healthy adults between the ages of 50 and 81
Dosage: 5 mg/week or 10 mg/week of rapamycin

One of the most potent anti-aging compounds rapamycin — an FDA-approved drug that inhibits mTOR — increases the lean body mass of older women while reducing their pain. 


Senior investigator Sajad Zalzala, MD (image: cnbc.com)

Search Result: visceral fat

Why Low Testosterone Isn’t Just About Getting Older: New U.S. Army Findings Point to Belly Fat

New Study Shows Increasing Mitochondrial Protein Improves Energy Production and Extends Lifespan

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

NAD+ Precursor NR Preserves Longevity-Promoting Cells, New Study Shows

Anti-Aging Drug Rapamycin Increases Muscle and Reduces Pain: New Results