A high but not low dose of nattokinase is associated with reducing artery plaque size by 36% in older adults. 

An ultrasound of the carotid artery with arrows pointing to plaques (image: avicennacardiology.com). 

Cardiovascular

A natural supplement, quercetin, targets age-promoting senescent cells, reduces inflammation, and counteracts blood vessel aging in men with heart disease. 

Study conducted at the University of Montreal in Quebec, Canada (image: ledevoir.com) 

Clinical Trials

A vaccine targeting an enzyme that breaks down NAD+, called CD38, counteracts signs of aging in mice. 


Immunity

<p>Model: 27-month-old male C57BL/6N mice </p>
<p>Dosage: 50 mg/kg/day of fisetin for 1 week, followed by no treatment for 2 weeks, followed by another week of treatment  </p>


Plant-based molecule fisetin preserves muscle mass and strength in older mice via senolytic action — removal of senescent (dysfunctional) cells.


Study conducted at the University of Colorado Boulder (image: govtech.com) 

Skin &amp; Muscle

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Search Result: vascular aging

New Study Reveals: High-Dose Supplement Shrinks Arterial Plaque by 36%

A Natural Senolytic Supplement Curbs Heart Aging in New Clinical Trial

Anti-Aging Vaccine Boosts Strength, Memory & NAD+ in New Study

Fisetin Fights Frailty: New Study Shows Supplment Preserves Strength

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age