Participants: Older adults with elevated HbA1c
Dosage: Nicotinamide (250 mg), palmitoylethanolamide (600 mg), oleoylethanolamide (400 mg), and spermidine (8 mg)

Supplement Combo that Mimics Fasting Counters Aging

In older adults, the combination of nicotinamide, palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and spermidine counters cardiovascular and metabolic aging. 

Study conducted by People Science Inc. (image: prnewswire.com)

Clinical Trials

NAD+ Ranked #2 Most Powerful Anti-Aging Agent

Based on current scientific evidence, Dutch researchers have ranked existing anti-aging interventions based on how likely they are to protect against DNA damage and aging. 


On the far right, one of the researchers, Dr. Jan H.J. Hoeijmakers (image: amazinggerasmusmc.nl). 

DNA Repair

Model: Young C57BL/6J mice fed a high protein (56% of daily calories) diet for 20 weeks 
Dosage: Injection with either 400 mg/kg of NMN or 20 mg/kg of 78c for 4 weeks

High protein intake improves the body composition of aged mice, but it lowers NAD+ (nicotinamide adenine dinucleotide) levels and promotes metabolic aging. 

Metabolism

Participants: Adults over the age of 60
Dosage: 3,750 mg of niacin twice daily (after gradual dose increase), 150 mg of dihydroberberine twice daily, 50 mg of taxifolin (with 500 mg of vitamin C and 15 mg of zinc) twice daily, 50 mg of tocotrienols twice daily

A combination of supplements, including the NAD+ precursor nicotinic acid, improves cholesterol, allowing some participants to cease taking statins.  

Study conducted by Professor Emeritus Joseph Keenan, MD, at the University of Minnesota. 

Nicotinic Acid

Does NAD+ (nicotinamide adenine dinucleotide) really help with aging? A team of international scientists reviews the latest and ongoing clinical trials.

Part of the research team, including Dr. Evandro Fei Fang (middle), from the University of Oslo and Akershus University Hospital in Norway (image: med.uio.no). 

Search Result: saturated fat

Supplement Combo that Mimics Fasting Counters Aging, New Study Shows

NAD+ Ranked #2 Most Powerful Way to Reverse DNA Damage & Aging

High Protein Intake Promotes Aging by Lowering NAD+ Levels

NAD+ Boosting Supplement Challenges Cholesterol-Lowering Statins in Anti-Aging Research

NAD+ and Aging: What the Latest Research Says