Model: Older adults (60–85 years old) with mild cognitive impairment (MCI) enrolled in a randomized, double-blind, placebo-controlled clinical trial.
Dosage: Participants received one gastro-resistant capsule daily for 180 days, containing either 250 mg of Kluyveromyces fragilis yeast extract, 350 mg of Saccharomyces cerevisiae yeast extract, or a placebo.

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

Daily supplementation with nucleotide-rich yeast extracts improves cognitive performance and mental well-being in older adults with mild cognitive impairment, researchers find. 

Brain &amp; Neurons

The NAD+ (nicotinamide adenine dinucleotide) precursor NR (nicotinamide riboside) counters sleep-deprivation-induced cognitive deficits in rats with excess Alzheimer’s plaques. 


Russia’s $27 Billion Bet on Beating Aging—Hype or Hope?

With an ambitious goal of conquering aging, Russia is investing $26 to $28 billion in a national health initiative.

(Russian leader, Vladimir Putin | RBC-Ukraine)

Aging &amp; Longevity

Top Evidence-Based Interventions to Lower Biological Age

Epigenetic aging clocks estimate biological age based on DNA molecular tagging patterns, and interventions like semaglutide and ketamine reduce these estimates in humans.

(The principal investigator behind the review on interventions that influence biological age, Dr. David Sinclair | The Society of the Four Arts)

As reviewed in this article, epigenetic aging clocks have estimated the effects of pharmaceutical interventions, lifestyle habits, supplements, and clinical interventions on biological age.

Japanese scientists have found that reducing NAD+ (nicotinamide adenine dinucleotide) transport into mitochondria within the fat tissue of mice induces metabolic dysregulation and obesity. 

Search Result: reducing age

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

NAD+ Booster Counters Cognitive Deficits of Sleep Deprivation, New Study Shows

Russia’s $27 Billion Bet on Beating Aging—Hype or Hope?

Top Evidence-Based Interventions to Lower Biological Age

NAD+ Transporter Prevents Obesity Caused by Aging: New Study Shows