Model: Chronically stressed mice 
Dosage: 9 mg/kg/day of L-serine, or 5 mg/kg/day of dasatinib combined with 50 mg/kg/day of quercetin

Supplementing chronically stressed mice with L-serine, an amino acid, counters signs of anxiety and diabetes while diverting age-promoting senescent cells within the brain’s fear center. 

Diabetes &amp; Obesity

Model: 8-month-old female Swiss mice
Dosage: 200 µL of aged-derived fecal suspension administered orally three days per week for two weeks

New Study: Transferring Gut Microbes from Old to Adult Mice Shortens Lifespan

Spanish scientists unveil data showing that transferring fecal microbes from old to adult mice increases biological age and shortens lifespan.

(A depiction of the intestines filled with gut microbes | Northwestern Medicine)

Spanish scientists show that transferring fecal microbes from old to adult mice increases biological age and shortens lifespan.

Aging &amp; Longevity

Aging Guru Bryan Johnson’s Supplement List for 2026

Changes to Bryan Johnson’s latest supplement stack include taking NMN or NR six days a week, rather than seven, and eliminating the use of rapamycin.

(Bryan Johnson, who utilizes a continuously updated protocol to slow aging and optimize his body | Netflix)

Changes to Bryan Johnson’s updated 2026 supplement stack include taking NMN or NR six days a week instead of seven and removing rapamycin.

Participants: Healthy middle-aged adults 
Dosage: 1200 mg/day of NR for 4 weeks

NR Raises NAD+ 2-Fold More than NMN

NR (nicotinamide riboside) raises blood NAD+ (nicotinamide adenine dinucleotide) levels more than NMN (nicotinamide mononucleotide) in healthy adults. 

Some of the researchers on the study, Dr. Christian Dölle (left) and Dr. Charalampos Tzoulis (middle) from the University of Bergen in Norway (image: uib.no). 

How to Boost Mitochondrial Tissue Density and Quality for Longevity

Lifestyle hacks contrived to promote the tissue density and quality of mitochondria (the cell’s powerhouses) can aid in the efficient generation of cellular energy and reduce inflammation, thereby promoting longevity.

(A colorized image of mitochondria taken with a transmission electron microscope | UC San Diego Today)

Exercise, nutritional support, and lifestyle hacks like cold exposure can all help mitigate mitochondrial dysfunction, a key hallmark of aging.

Search Result: nervous system

Cheap Supplement May Counter Stress-Induced Diabetes, Anxiety, and Brain Senescence, According to New Study

New Study: Transferring Gut Microbes from Old to Adult Mice Shortens Lifespan

Aging Guru Bryan Johnson’s Supplement List for 2026

NR Raises NAD+ Over 2-Fold More than NMN: New Study Comparing NAD+ Precursors

How to Boost Mitochondrial Tissue Density and Quality for Longevity