The theory says our brain allocates resources to energy-consuming senescent cells at the body’s expense, accounting for gray hair, muscle shrinkage, and other signs of aging.

Aging &amp; Longevity

Supplements like NAD+ boosters may benefit older individuals, while drugs like metformin and interventions such as physical exercise may not, according to German scientists. 

A 167-study analysis reveals that rapamycin prolongs lifespan as effectively as dietary restriction: reducing food intake without entering a state of malnourishment.

<p>Model: C3B6F1 hybrid mice<br />
Dosage: 42 mg/kg of rapamycin and 1.44 mg/kg of trametinib in food starting at 6 months of age</p>


Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

(The study’s lead author, Linda Partridge | The Biologist)

Combining two cancer treatment drugs, trametinib and rapamycin, extends lifespan by 29% and 27% in middle-aged female and male mice, respectively.

German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals. 

Search Result: mTOR

Are Senescent Cells Turning Your Hair Gray? A New Aging Theory

New Findings: Anti-Aging Supplements Are Not “One-Size-Fits-All”

Anti-Aging Drug Rapamycin Extends Life as Much as Dieting, New Study Shows

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Longevity Secrets in Your Genome: Hidden mTOR Variants Identified