German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals. 

Aging &amp; Longevity

Removing an NAD+ transporter called SLC25A51 from insulin-secreting cells mitigates diabetes and reduces senescent cells — cells that contribute to the pathology of age-related diseases.  


Principal investigator Nora Kory, PhD, from Harvard University (image: harvard.edu). 

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

With over 246 million data points, obtained from 108 participants, scientists show that we rapidly age around 45 and 60. 

Stanford researchers find that our biological age accelerates during mid-life and retirement age. 

Model: UM-HET3 mice
Dosage: Astaxanthin was fed at 4,000 ppm in the diet beginning after weaning
Meclizine was fed at 800 ppm in the diet beginning after weaning
Administering fisetin started at 20 months old and was fed continuously or a repeated cycle of three days on and 11 days off at a target of 600 ppm in the diet

Over-the-Counter Wonders: New Research Highlights Two Compounds for a Longer Life

A consortium that examines longevity interventions in mice has found that the anti-nausea compound meclizine as well as the antioxidant astaxanthin extend male mouse lifespan.

(A long-lived mouse surrounded by potential lifespan-extending compounds | NAD.com)

A consortium of researchers has identified the anti-seasickness drug meclizine and the antioxidant astaxanthin as two compounds that significantly extend male mouse lifespan.

Search Result: mRNA

Longevity Secrets in Your Genome: Hidden mTOR Variants Identified

Harvard Scientists Unravel the Role of NAD+ Transporter in Mitigating Age-Related Diabetes

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Epic New Stanford Study Reveals Two Critical Phases of Rapid Aging in Our Lifetime

Over-the-Counter Wonders: New Research Highlights Two Compounds for a Longer Life