Model: Otherwise healthy adults aged 40 and older
Dosage: 15 g of the multi-ingredient supplement dissolved in up to 500 mL of water or juice, given each day orally for six months

Can a Nutritional Supplement Prevent Vascular Aging? 6-Month Human Trial Results

A six-month human trial found that a multi-ingredient nutritional supplement improved vascular health, reducing arterial stiffness and lowering systolic blood pressure.

(An image depicting increased arterial stiffness [measured with pulse-wave velocity] and blood pressure, along with reduced flow-mediated dilation in aged blood vessels | NAD.com)

A six-month randomized trial found that a multi-ingredient supplement improved vascular health markers, including arterial stiffness and blood pressure.

Cardiovascular

University of Southern California (USC) scientists help to uncover why human intelligence declines with age, pointing to a newly discovered cellular target.


The principal investigator on the study, Dr. Michael Bonaguidi (image: usc.edu).

Brain &amp; Neurons

Model: Eight-week-old C57BL/6J mice treated with 300 mg/kg/day of D-galactose by subcutaneous injections for eight weeks
Dosage: 100 mg/kg/day of NMN in drinking water for eight weeks and 5 × 10 5 hUC-MSCs suspended in 150 µL of PBS via tail vein injection on the first day of weeks five through seven

NMN Enhances Stem Cell Therapy’s Effects on Immune Aging in Latest Study

Combining NMN with umbilical cord–derived stem cells improved motor and cognitive function while reducing markers of immune aging in mice with chemically induced aging.

(An image of human umbilical cord-derived mesenchymal stem cells under a microscope | NAD.com)

NMN with a stem cell therapy reduced markers of immune aging and improved coordination and memory performance in mice with chemically induced aging-like changes.

Immunity

A new scientific review questions how much researchers actually know about fasting’s ability to enhance cellular recycling—particularly in humans.

The spherical structure depicts an autophagolysosome. 

Aging &amp; Longevity

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

University of Wisconsin researchers examine how reducing dietary protein intake may reshape nutrient sensing, metabolism, mitochondrial function, and other pathways linked to healthier aging.

(One of the leading authors on the Cell Press Blue article, Dr. Dudley Lamming | University of Wisconsin)

Researchers examine how restricting protein intake can improve metabolic health and influence aging-related pathways to extend healthspan and lifespan.

Search Result: increasing lifespan

Can a Nutritional Supplement Prevent Vascular Aging? 6-Month Human Trial Results

What Causes Age-Related Intelligence Decline? A New Study Points to Immature Brain Cells

NMN Enhances Stem Cell Therapy’s Effects on Immune Aging in Latest Study

Does Fasting Really Trigger Autophagy? New Study Challenges Popular Longevity Belief

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?