Model: Male ApoE−/− mice fed a high-fat diet for 12 weeks to induce atherosclerosis.
Dosage: Methyl-β-cyclodextrin (Mß-CD) at 2.0 g/kg, subcutaneous injection, twice a week

 A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death. 

Cardiovascular

Participants: Healthy middle-aged to older adults (average age: ~53 years) 
Dosage: 1,000 mg/day of urolithin A for 28 days

Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations. 

Columbia University in New York City (image: Columbia.edu). 

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

NAD+ (nicotinamide adenine dinucleotide) may contribute to healthy cellular aging by enhancing biological energy flow, according to the newly formulated energy resistance principle.


Search Result: heart

Scientists Find a New Way to Stop Dangerous Artery Plaques From Growing

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

The Inflammation Myth: New Insights on Aging

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Boosting NAD+ May Defy Aging by Enhancing Energy Flow, According to a New Theory