Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

(Dr. David Sinclair believes an age-reversing pill is under development | YouTube)

Harvard’s Dr. David Sinclair believes an age-reversing pill may become available within a decade and that researchers may find a way to one day double human lifespan.

Aging &amp; Longevity

Model: C3B6F1 hybrid mice 
Dosage: 42 mg/kg of rapamycin and 1.44 mg/kg of trametinib in food starting at 6 months of age

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

(The study’s lead author, Linda Partridge | The Biologist)

Combining two cancer treatment drugs, trametinib and rapamycin, extends lifespan by 29% and 27% in middle-aged female and male mice, respectively.

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Cornell and UPenn scientists find that mice introduced to the wild as infants age faster than lab mice, but what does this mean for humans?


Epigenetics

Model: 24-month-old male and female C57BL/6J mice
Dosage: 3 mg/kg/day, delivered continuously over 8 weeks

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals

Scientists show that elamipretide restores muscle and heart function in aging mice but doesn’t affect epigenetic or transcriptomic age.


Search Result: epigenetic age

Anti-Aging Breakthrough? Harvard’s David Sinclair Predicts Age-Reversing Pill by 2035

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

Do Humans Age Like Mice? New Study Reveals Surprising Similarities

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals