Aging Guru Bryan Johnson’s Supplement List for 2026

Changes to Bryan Johnson’s latest supplement stack include taking NMN or NR six days a week, rather than seven, and eliminating the use of rapamycin.

(Bryan Johnson, who utilizes a continuously updated protocol to slow aging and optimize his body | Netflix)

Changes to Bryan Johnson’s updated 2026 supplement stack include taking NMN or NR six days a week instead of seven and removing rapamycin.

Aging &amp; Longevity

Model: Middle-aged cynomolgus monkeys
Dosage: 30 mg/kg/day of vitamin C, orally administered for 40 months

Vitamin C Alleviates Aging in Monkeys

Vitamin C improves brain volume and connectivity, reduces biological age, enhances metabolic health, and alleviates underlying aging drivers, such as cellular senescence, in older monkeys. 

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

A naturally occurring compound, α-lipoic acid, helped elderly mice think like younger mice by restoring energy balance and calming brain inflammation, according to Second Hospital of Hebei Medical University researchers.

(Alpha-lipoic acid’s molecular structure | Sasha’s of Saratoga)

Brain &amp; Neurons

Participants: Healthy overweight adults between the ages of 45 and 55 
Dosage: 3 grams/day of ginseng for 28 days

Ginseng Boosts NAD+ and Telomeres: New Study in Middle-Aged Adults

Ginseng supplementation boosts NAD+ (nicotinamide adenine dinucleotide) and lengthens telomeres in middle-aged adults, suggesting an amelioration of aging. 


Panax ginseng Meyer (image: farmaimpresa.com).

Approved Human Study Sets Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

In a major proving ground test for the longevity field, the FDA has given its approval for a human trial for a gene therapy attempting a near-total rejuvenating reset of cells.

(David Sinclair, Michael Ringel, Sharon Rosenzweig-Lipson, and Jerry McLaughlin of Life Biosciences | Longevity.technology)

The FDA has greenlighted Life Biosciences’ first human trial testing whether their gene therapy can confer a near-total rejuvenating reset of cells.

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Aging Guru Bryan Johnson’s Supplement List for 2026

Vitamin C Alleviates Aging in Monkeys, New Study Shows

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

Ginseng Boosts NAD+ and Telomeres: New Study in Middle-Aged Adults

FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair