Pioneering expert in NAD+ metabolism, Shin-Ichiro Imai, MD, PhD, explains the critical role of NAD+ in preventing chronic kidney disease, the ninth leading cause of death worldwide. 


Dr. Shin-Ichiro Imai (image: mspremium.com)

After accounting for previously unaddressed issues, researchers find that human lifespan is over 50% heritable, challenging previous estimates of 25%.  


Joris Deelen, PhD, one of the researchers on the project (image: stern.de).

Aging &amp; Longevity

Model: Naturally aged C57BL/6J mice

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

A new study provides data suggesting compromised intestinal function with age and that fasting for short periods promotes intestinal regeneration and function in aged mice.

(A dysfunctional intestinal barrier that leaks harmful substances and bacteria into circulation develops with age | The Amino Company)

Alternate-day fasting, a form of intermittent fasting, reverses age-related intestinal barrier leakage in old mice.

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL. 

The participants of the study were from Sardinia, Italy (image: businessinsider.com). 

Metabolism

Model: 10-month-old and 22-month-old naturally aged mice / Rats with Partial Discectomy (PDE)-induced Temporomandibular Joint Osteoarthritis (TMJOA).
Dosage: 0.25% αKG and  0.75% αKG
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Longevity Compound Thwarts Age-Related Joint Degeneration: New Study Reveals

Researchers found that alpha-ketoglutarate (αKG) can treat osteoarthritis by preserving cartilage and reducing joint inflammation. 

Search Result: death

Expert Explains Role of NAD+ in Preventing Age-Related Kidney Disease

New Study Shows Lifespan is 50% Genetic, Doubling Previous Estimates

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

New Study Shows People with Higher Cholesterol Live Longer than People with Lower Cholesterol

Longevity Compound Thwarts Age-Related Joint Degeneration: New Study Reveals