Implanting DNA “rivers” into older mice significantly extends their lifespan and reduces age-promoting senescent cells in multiple vital organs. 

Professor of Molecular Immunology at Oxford University, and one of the researchers on the study, Dr. Michael Dustin (image: kennedy.ox.ac.uk). 

DNA Repair

Approved Human Study Sets Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

In a major proving ground test for the longevity field, the FDA has given its approval for a human trial for a gene therapy attempting a near-total rejuvenating reset of cells.

(David Sinclair, Michael Ringel, Sharon Rosenzweig-Lipson, and Jerry McLaughlin of Life Biosciences | Longevity.technology)

The FDA has greenlighted Life Biosciences’ first human trial testing whether their gene therapy can confer a near-total rejuvenating reset of cells.

Clinical Trials

Elon Musk Says Figuring Out How to Reverse Aging ‘Highly Likely’

The business magnate and SpaceX CEO, Elon Musk, now believes that death is a kind of engineering bug that determined aging scientists can eventually fix.

The high-profile American entrepreneur, Elon Musk, now says figuring out human lifespan extension is highly likely.

Aging &amp; Longevity

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

Bryan Johnson debates 20 skeptics on anti-aging in Jubilee’s viral episode and challenges assumptions about lifespan, science, and the future of human health.


Model: Male COX7RP transgenic mice with systemic overexpression of COX7RP, aged under standard laboratory conditions and compared with age-matched wild-type controls.
Dosage: Not applicable. COX7RP activity was increased via genetic overexpression rather than drug administration.

Boosting mitochondrial efficiency by increasing COX7RP activity extended lifespan in mice while improving energy production and reducing inflammation.

Search Result: biological aging

Newly Discovered DNA “Rivers” More Than Double Lifespan: Oxford University

FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

Elon Musk Says Figuring Out How to Reverse Aging ‘Highly Likely’

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

New Study Shows Increasing Mitochondrial Protein Improves Energy Production and Extends Lifespan