Model: Male C57BL/6J (B6) mice (15 months old at the start of treatment)
Dosage: Approximately 5 mg/kg/day of S-1-propenyl-L-cysteine (S1PC) was administered orally for 8 months, from 15 to 23 months of age. S1PC was given in chow containing 0.0025% S1PC, with a second experiment using drinking water to confirm the findings.

Researchers found that a compound found in garlic supports healthier muscle aging by boosting cellular defenses linked to longevity and maintaining physical performance.

Skin &amp; Muscle

Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The XPrize Healthspan—which will split $101 million among teams developing therapeutics to restore muscle, cognitive, and immune function in older adults—has named 10 teams receiving $1 million each.

(XPrize announced the finalists for its XPrize Healthspan competition | XPrize)

The XPrize Healthspan competition has named its top 20 finalist groups that will submit their aging intervention therapies for human trial testing.

Aging &amp; Longevity

NAD+ Ranked #2 Most Powerful Anti-Aging Agent

Based on current scientific evidence, Dutch researchers have ranked existing anti-aging interventions based on how likely they are to protect against DNA damage and aging. 


On the far right, one of the researchers, Dr. Jan H.J. Hoeijmakers (image: amazinggerasmusmc.nl). 

DNA Repair

Model: Male C57BL/6J mice
Dosage: 150 mg/kg/day of diallyl sulforated compounds in food

Diallyl sulfonated compounds (DAS), found in garlic, extend the lifespan of mice while counteracting signs of aging, such as grip weakness and memory loss. 

Dr. Vivian Capilla-González, one of the researchers on the study (image: cde.ual.es).

Model: 20-month-old male C57BL/6 mice 
Dosage: 3,000 to 4,000 µg of ouabain dissolved in 27,000 to 36,000 µL of PBS injected twice per week every third week over a period of three months

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

Harvard and MIT scientists analyze decades of publicly available molecular studies with a new AI platform to uncover hundreds of previously hidden anti-aging strategies, like the drug ouabain.

A new AI platform has uncovered hundreds of pro-longevity agents based on the reanalysis of millions of mouse and human gene expression samples.

Search Result: anti-aging supplements

Garlic-Derived Compound Activates a Natural Anti-Aging Pathway That Preserves Muscle Function

10 Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

NAD+ Ranked #2 Most Powerful Way to Reverse DNA Damage & Aging

Garlic Compound Extends Life, Builds Strength, and Boosts Memory, New Study Shows

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions