Participants: Older adults with elevated HbA1c
Dosage: Nicotinamide (250 mg), palmitoylethanolamide (600 mg), oleoylethanolamide (400 mg), and spermidine (8 mg)

Supplement Combo that Mimics Fasting Counters Aging

In older adults, the combination of nicotinamide, palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and spermidine counters cardiovascular and metabolic aging. 

Study conducted by People Science Inc. (image: prnewswire.com)

Clinical Trials

NAD+ Ranked #2 Most Powerful Anti-Aging Agent

Based on current scientific evidence, Dutch researchers have ranked existing anti-aging interventions based on how likely they are to protect against DNA damage and aging. 


On the far right, one of the researchers, Dr. Jan H.J. Hoeijmakers (image: amazinggerasmusmc.nl). 

DNA Repair

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

Bryan Johnson debates 20 skeptics on anti-aging in Jubilee’s viral episode and challenges assumptions about lifespan, science, and the future of human health.


Aging &amp; Longevity

Participants: Adults over the age of 60
Dosage: 3,750 mg of niacin twice daily (after gradual dose increase), 150 mg of dihydroberberine twice daily, 50 mg of taxifolin (with 500 mg of vitamin C and 15 mg of zinc) twice daily, 50 mg of tocotrienols twice daily

A combination of supplements, including the NAD+ precursor nicotinic acid, improves cholesterol, allowing some participants to cease taking statins.  

Study conducted by Professor Emeritus Joseph Keenan, MD, at the University of Minnesota. 

Nicotinic Acid

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Search Result: anti-aging benefits

Supplement Combo that Mimics Fasting Counters Aging, New Study Shows

NAD+ Ranked #2 Most Powerful Way to Reverse DNA Damage & Aging

The Anti-Aging Debate Everyone’s Talking About: Inside Bryan Johnson’s Jubilee Showdown

NAD+ Boosting Supplement Challenges Cholesterol-Lowering Statins in Anti-Aging Research

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits