Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

University of Wisconsin researchers examine how reducing dietary protein intake may reshape nutrient sensing, metabolism, mitochondrial function, and other pathways linked to healthier aging.

(One of the leading authors on the Cell Press Blue article, Dr. Dudley Lamming | University of Wisconsin)

Researchers examine how restricting protein intake can improve metabolic health and influence aging-related pathways to extend healthspan and lifespan.

Aging &amp; Longevity

Life Biosciences reports preliminary visual-field improvements in two of three glaucoma patients treated with the experimental therapy developed by Dr. David Sinclair’s Harvard team, ER-100.

Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The XPrize Healthspan—which will split $101 million among teams developing therapeutics to restore muscle, cognitive, and immune function in older adults—has named 10 teams receiving $1 million each.

(XPrize announced the finalists for its XPrize Healthspan competition | XPrize)

The XPrize Healthspan competition has named its top 20 finalist groups that will submit their aging intervention therapies for human trial testing.

Model: Female Balb/c mice exposed to ultraviolet radiation 
Dosage: 2%, 5%, 7.5%, or 12.5% of nicotinamide (weight/volume) applied topically, once daily, five times per week

The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide prevents skin aging, in part by targeting age-promoting senescent cells in mice. 


Top Evidence-Based Interventions to Lower Biological Age

Epigenetic aging clocks estimate biological age based on DNA molecular tagging patterns, and interventions like semaglutide and ketamine reduce these estimates in humans.

(The principal investigator behind the review on interventions that influence biological age, Dr. David Sinclair | The Society of the Four Arts)

As reviewed in this article, epigenetic aging clocks have estimated the effects of pharmaceutical interventions, lifestyle habits, supplements, and clinical interventions on biological age.

Search Result: UV light

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

David Sinclair’s Experimental Cell-Rejuvenation Therapy Shows Early Vision Signals in First Human Trial

10 Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

NAD+ Booster Nicotinamide Counters Skin Aging and Cell Senescence, New Study Shows

Top Evidence-Based Interventions to Lower Biological Age