Model: Cybrids composed of Rho0 cells with human platelet mitochondrial DNA from participants between 7 days old and 99 years old 
Dosage: 5 mM of n-Acetyl-L-Cysteine and 3 mM of nicotinamide riboside, with medium changed every three days until the cell population reached between 1 and 10 million

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

(Telomeres [highlighted in gold] at the ends of a chromosome | NAD.com)

A new study suggests the NAD+ precursor NR combined with the antioxidant NAC may counteract telomere shortening, a hallmark of aging.

Aging &amp; Longevity

Participants: Healthy middle-aged adults (average age: 55)
Dosage: 100 mg/day of Monarda didyma L. extract, preferably at lunchtime with plenty of water, for 12 weeks

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life. 

A flower from the Monarda didyma L. plant (image: nativeplanttrust.org) 

Clinical Trials

Is Hyperbaric Oxygen Therapy A Rip-off?

Many longevity clinics are popping up across the world, and celebrities are promoting the lifespan-extension fad, sometimes for up to tens of thousands of dollars.

(A woman undergoing hyperbaric oxygen therapy | Northwestern Medicine)

NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts

Dr. Peter Attia shares his thoughts on NAD+ precursors, their potential impact on aging and longevity, and the importance of further research in this field.

Six Intriguing Ideas from David Sinclair’s Book, Lifespan

In his book, Harvard’s Dr. David Sinclair presents concepts such as the Information Theory of Aging — how modifications to our DNA may cause aging.

(Lifespan: Why We Age — and Why We Don’t Have To | booko.com.au)

Harvard’s Dr. David Sinclair presents six thrilling ideas in his book Lifespan, which include his Information Theory of Aging — changes to chemical modifications on DNA that underlie all aging processes.

Search Result: Telomeres

New Study: Combining NR with NAC May Slow Telomere Shortening

Flower Extract Slows Cellular Aging, New Study Shows

Is Hyperbaric Oxygen Therapy A Rip-off?

NAD+ Precursors, Aging, and Longevity: Dr. Peter Attia’s Thoughts

Six Intriguing Ideas from David Sinclair’s Book, Lifespan: Why We Age — and Why We Don’t Have To