Participants: Healthy males (age range: 70-76)
Dosage: 1 mg/kg/day of rapamycin for 8 weeks

Supplementing with rapamycin leads to improvements in cardiac and vascular function in older men, suggesting this longevity-associated drug may counteract cardiovascular aging. 

Nicolas Musi, MD, professor of medicine and an author of the study (image: sanantoniomag.com). 

Cardiovascular

Older adults with LDL cholesterol levels above 130 mg/dL live longer than older adults with LDL cholesterol levels below 130 mg/dL. 

The participants of the study were from Sardinia, Italy (image: businessinsider.com). 

Metabolism

Activist Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins

Dr. Aseem Malhotra, a cardiologist from the UK, says pharmaceutical company-sponsored research distorts the scientific evidence behind the effectiveness of cholesterol-lowering statins against heart disease.

(Dr. Aseem Malhotra, cardiologist | The Telegraph)

Participants: Healthy older adults 
Dosage: 4 × 5 g/day of creatine monohydrate for 5 days, followed by 1 × 5 g/day for 23 days

Creatine improves vascular health while lowering blood glucose and triglyceride levels in older adults.

NAD+ is not the same as vitamin B3. However, NAD+ is considered the bioactive form of vitamin B3 because vitamin B3 is converted to NAD+ in the body. 


The main purpose of vitamin B3 is to maintain NAD+ levels. 

Search Result: Statins

Longevity Drug Rapamycin Improves the Heart of Older Adults, New Study Shows

New Study Shows People with Higher Cholesterol Live Longer than People with Lower Cholesterol

Activist Cardiologist Says Commercial Interests Are Distorting Evidence Behind Statins

New Pilot Study Reveals That Creatine Improves Heart Health

Is NAD+ the Same as Vitamin B3?