Seragon Biosciences has launched its new sleep and longevity optimizer, Enlivien, featuring technology based on a Harvard University collaboration. 


Aging &amp; Longevity

The theory says our brain allocates resources to energy-consuming senescent cells at the body’s expense, accounting for gray hair, muscle shrinkage, and other signs of aging.

A natural supplement, quercetin, targets age-promoting senescent cells, reduces inflammation, and counteracts blood vessel aging in men with heart disease. 

Study conducted at the University of Montreal in Quebec, Canada (image: ledevoir.com) 

Clinical Trials

Model: 27-month-old male C57BL/6N mice 
Dosage: 50 mg/kg/day of fisetin for 1 week, followed by no treatment for 2 weeks, followed by another week of treatment

Plant-based molecule fisetin preserves muscle mass and strength in older mice via senolytic action — removal of senescent (dysfunctional) cells.


Study conducted at the University of Colorado Boulder (image: govtech.com) 

Skin &amp; Muscle

Model: C3B6F1 hybrid mice 
Dosage: 42 mg/kg of rapamycin and 1.44 mg/kg of trametinib in food starting at 6 months of age

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

(The study’s lead author, Linda Partridge | The Biologist)

Combining two cancer treatment drugs, trametinib and rapamycin, extends lifespan by 29% and 27% in middle-aged female and male mice, respectively.

Search Result: Senolytic

Enlivien: A New Dawn for Sleep and Longevity

Are Senescent Cells Turning Your Hair Gray? A New Aging Theory

A Natural Senolytic Supplement Curbs Heart Aging in New Clinical Trial

Fisetin Fights Frailty: New Study Shows Supplment Preserves Strength

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan