The most comprehensive brain model reveals that combining NAD+ (nicotinamide adenine dinucleotide) supplementation with diet and exercise powerfully modulates brain aging. 


Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025

Aging guru Bryan Johnson shares his latest daily longevity protocol, which he uses to optimize measurements of his body’s aging.

(A futuristic image of Bryan Johnson | YouTube)

Venture capitalist and aging guru Bryan Johnson reveals his latest longevity-focused daily routine for 2025, focusing on sleep, exercise, and eating well.

Aging &amp; Longevity

<p>Model: C57BL/6N mice<br />
Dosage: 1 g/kg carvedilol in food for one week followed by four weeks of PAGln treatment, consisting of 50 mg/kg per day by injection, and the same PAGln treatment for four weeks followed by 50 mg/kg per day of ABT263 via oral gavage for five days</p>


New Study Suggests Combining Senolytics with Blood Pressure Medication Counteracts an Aging Gut

Carvedilol, a blood pressure medication, and the senolytic agent ABT-263 both attenuate cellular senescence—an age-related, dysfunctional cellular state—driven by a gut bacterial metabolite in mice.

Transplanting a population of “young” stem cells from old mice prolongs the lifespan of middle-aged mice and delays manifestations of aging. 

Is Hyperbaric Oxygen Therapy A Rip-off?

Many longevity clinics are popping up across the world, and celebrities are promoting the lifespan-extension fad, sometimes for up to tens of thousands of dollars.

(A woman undergoing hyperbaric oxygen therapy | Northwestern Medicine)

Search Result: Oxygen Therapy

Most Comprehensive Study Places NAD+ at Forefront of Countering Brain Aging

Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025

Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study

New Study Shows Stem Cells Stop Aging and Prolong Life

Is Hyperbaric Oxygen Therapy A Rip-off?