The plant-based compound Harmine counteracts the cellular aging triggered by sleep deprivation in animal models and human cells.

Study conducted at the Leibniz Institute on Aging. 

Aging &amp; Longevity

Seragon Biosciences has launched its new sleep and longevity optimizer, Enlivien, featuring technology based on a Harvard University collaboration. 


Supplements like NAD+ boosters may benefit older individuals, while drugs like metformin and interventions such as physical exercise may not, according to German scientists. 

Model: Cybrids composed of Rho0 cells with human platelet mitochondrial DNA from participants between 7 days old and 99 years old 
Dosage: 5 mM of n-Acetyl-L-Cysteine and 3 mM of nicotinamide riboside, with medium changed every three days until the cell population reached between 1 and 10 million

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

(Telomeres [highlighted in gold] at the ends of a chromosome | NAD.com)

A new study suggests the NAD+ precursor NR combined with the antioxidant NAC may counteract telomere shortening, a hallmark of aging.

Participants: Healthy middle-aged adults (average age: 55)
Dosage: 100 mg/day of Monarda didyma L. extract, preferably at lunchtime with plenty of water, for 12 weeks

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life. 

A flower from the Monarda didyma L. plant (image: nativeplanttrust.org) 

Search Result: Oxidative Stress

Scientist May Have Discovered a New Drug that Makes Up for Lost Sleep

Enlivien: A New Dawn for Sleep and Longevity

New Findings: Anti-Aging Supplements Are Not “One-Size-Fits-All”

New Study: Combining NR with NAC May Slow Telomere Shortening

Flower Extract Slows Cellular Aging, New Study Shows