Model: SAMP8 mice (5 months old) and C57BL/6 mice (16 months old)
Dosage: 1.5 mg/kg of urolithin A was administered by intraperitoneal injection three times per week (Monday, Wednesday, and Friday) for 8 weeks.

Study shows that urolithin A preserves memory and cognitive function during aging when treatment begins before age-related decline, but does not reverse cognitive impairment once it is established.

Brain &amp; Neurons

Bryan Johnson’s “Clone”: Where the Sci-Fi Ends and the Science Begins

The biohacker says his “newborn” clone could supply young blood, test experimental treatments, and eventually grow replacement organs.

(Bryan Johnson says he’s cloned himself, which could supply young blood, help test experimental treatments, and eventually grow replacement organs. | Futurism)

Aging &amp; Longevity

By examining chemical tags on DNA that modulate our genes, scientists have discovered which genes are most affected by aging across more than a dozen human tissues.

The study was led by Dr. Nir Eynon from the Australian Regenerative Medicine Institute (image: vu.edu.au). 

Epigenetics

Model: Male Wistar rats 
Dosage: 1.5 g/kg/day of orally administered glycine for 5 months

Glycine, an amino acid shown to extend the lifespan of mice, moderately extends the lifespan of flies and counters brain and muscle degeneration in aged rats. 

Model: Older adults (60–85 years old) with mild cognitive impairment (MCI) enrolled in a randomized, double-blind, placebo-controlled clinical trial.
Dosage: Participants received one gastro-resistant capsule daily for 180 days, containing either 250 mg of Kluyveromyces fragilis yeast extract, 350 mg of Saccharomyces cerevisiae yeast extract, or a placebo.

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

Daily supplementation with nucleotide-rich yeast extracts improves cognitive performance and mental well-being in older adults with mild cognitive impairment, researchers find. 

Search Result: Neurons

Urolithin A Preserves Memory During Aging When Treatment Begins Early, Study Shows

Bryan Johnson’s “Clone”: Where the Sci-Fi Ends and the Science Begins

Scientists Find a Gene That Is Altered Across All Tissues Tested

Glycine Extends Life & Counters Brain and Muscle Degeneration, New Study Shows

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment