<p>Model: Healthy adults between 21 and 79 years of age<br />
Dosage: 395 mg/kg of bodyweight of (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate monoester (𝛽-hydroxybutyrate ketones) diluted in water and administered once</p>


New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

A new study suggests that supplementing with ketones—molecules the body can use for energy when lacking sugars—prevents cognitive aging when administered in people’s 40s and 50s.

(The study’s principal investigator, Dr. Lilianne R. Mujica-Parodi | Stony Brook University News)

Based on age-related destabilized brain signaling, a new study suggests a critical midlife window where metabolic interventions may stabilize brain signaling.

Brain &amp; Neurons

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years

Worldwide, people consume about 2 billion cups of coffee a day, and a new review associates drinking this caffeinated beverage regularly with an average of 1.8 years added to lifespan.

Aging &amp; Longevity

With over 246 million data points, obtained from 108 participants, scientists show that we rapidly age around 45 and 60. 

Stanford researchers find that our biological age accelerates during mid-life and retirement age. 

Combining Micronutrients with NAD+ Precursors to Maximize Their Effects

Mixing nutraceutical molecules with nicotinamide adenine dinucleotide (NAD+) precursors may synergistically boost and maintain NAD+ levels while bolstering their longevity-promoting benefits.

(An aged individual’s hand alongside a younger person’s hand, each holding different types of supplement capsules | NAD.com)

Combining nutraceuticals with NAD+ precursors may be a potent way to boost and maintain NAD+ levels while promoting other anti-aging benefits.

Reviews

Metabolic Regulators: Improving Energy Production and Expenditure

Metabolic modulators like rapamycin, urolithin A, acarbose, glycine and N-acetyl cysteine, and canagliflozin enhance mitochondrial function to improve metabolism to increase longevity.

(A mitochondria surrounded by a canagliflozin molecule [top left], an acarbose molecule [bottom left], and an N-acetyl cysteine molecule [bottom right])

Explore the impact of metabolic regulators on energy production and expenditure. Discover how these regulators influence cellular metabolism and potentially contribute to improved energy balance and overall health at NAD.com.

Search Result: Lipid Metabolism

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years

Epic New Stanford Study Reveals Two Critical Phases of Rapid Aging in Our Lifetime

Enhancing Longevity-Promoting Cocktails: Combining Micronutrients with NAD+ Precursors to Maximize Their Effects

Metabolic Regulators: Extending Lifespan by Modulating Energy Production and Mitigating Cell Damage