Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Participants: healthy adults between the ages of 50 and 81
Dosage: 5 mg/week or 10 mg/week of rapamycin

One of the most potent anti-aging compounds rapamycin — an FDA-approved drug that inhibits mTOR — increases the lean body mass of older women while reducing their pain. 


Senior investigator Sajad Zalzala, MD (image: cnbc.com)

Clinical Trials

Model: 3-month-old LDLR−/− pigs
Dosage: 400 nM of SWNT or SWNT-SHP1i 
was infused intravenously for ~15–30 min, once a week, for 12 weeks

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis 

Stanford School of Medicine researchers develop safe nanoparticles that target dying cells in atherosclerotic plaque and reduce vascular inflammation.

Cardiovascular

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength

Betaine prevents loss of muscle mass and strength while enhancing autophagy in old mice.

Skin &amp; Muscle

Want to Get Fit? Look at What Sylvester Stallone Does at 78

Sylvester Stallone’s daily diet includes egg whites as well as broiled chicken and fish for plenty of protein, and his most current workouts focus on the chest, back, abs, and legs for optimal longevity.

(Even at age 78, Sylvester Stallone maintains a strikingly cut physique | YouTube)

Search Result: Lean Mass

Longevity Prescription

Anti-Aging Supplement Rapamycin Increases Muscle and Reduces Pain: New Results

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis

Betaine Supplement Prevents Age-Related Loss of Muscle Size and Strength

Want to Get Fit? Look at What Sylvester Stallone Does at 78