Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Aging &amp; Longevity

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


NAD+ Supercharges Immune System Recovery in Older Mice

Researchers from the University of California, Berkeley, found that young mice need NAD+ breakdown, while old mice need NAD+ boosting.

Immunity

The NAD+-consuming enzyme CD38 is elevated in individuals predisposed to Alzheimer’s, and blocking it improves the metabolic health and cognition of mice that model Alzheimer’s. 


Principal investigator Michal Shwartz, PhD (Image: Jonathan Bloom).

Search Result: Immunity

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

Longevity Prescription

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice

Blocking NAD+ Breakdown Improves Brain Fitness and Cognition, New Study Shows