Based on current scientific evidence, Dutch researchers have ranked existing anti-aging interventions based on how likely they are to protect against DNA damage and aging. 


On the far right, one of the researchers, Dr. Jan H.J. Hoeijmakers (image: amazinggerasmusmc.nl). 

DNA Repair

How to Boost Mitochondrial Density and Quality for Longevity

Lifestyle hacks contrived to promote the tissue density and quality of mitochondria (the cell’s powerhouses) can aid in the efficient generation of cellular energy and reduce inflammation, thereby promoting longevity.

(A colorized image of mitochondria taken with a transmission electron microscope | UC San Diego Today)

Exercise, nutritional support, and lifestyle hacks like cold exposure can all help mitigate mitochondrial dysfunction, a key hallmark of aging.

Aging &amp; Longevity

How to Support Muscle Function with Age: Top Evidence-Based Supplements

Data suggest certain supplements, such as L-carnitine, vitamin D, and essential minerals, support muscle function and physical performance in adults of advanced age.

Researchers from University College London review data supporting that supplements, like vitamin D, L-carnitine, and essential minerals, support muscle function during aging.

Skin &amp; Muscle

<p>Participants: Healthy middle-aged to older adults (average age: ~53 years)</p>
<p>Dosage: 1,000 mg/day of urolithin A for 28 days</p>


Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

The interventions that may help fix or reset circadian rhythms, which decline with age. 

A representation of Kairos, not to be confused with Kronos (original image: misel-trogir.com).

Search Result: Gut health

NAD+ Ranked #2 Most Powerful Way to Reverse DNA Damage & Aging

How to Boost Mitochondrial Density and Quality for Longevity

How to Support Muscle Function with Age: Top Evidence-Based Supplements

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

Beyond Aligning Life with Light: Supplements that Counter Circadian Decline