Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Aging &amp; Longevity

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Restoring the essential molecule NAD+ may potentially hold the key to treating Alzheimer’s, as Harvard researchers emphasize the role of low brain NAD+ in this devastating disease.


Brain &amp; Neurons

University of California, Irvine (UCI) scientists identify a NAD+ precursor in mice that declines with age and mitigates age-related kidney decline.


<p>Model: Healthy adults between 21 and 79 years of age<br />
Dosage: 395 mg/kg of bodyweight of (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate monoester (𝛽-hydroxybutyrate ketones) diluted in water and administered once</p>


New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

A new study suggests that supplementing with ketones—molecules the body can use for energy when lacking sugars—prevents cognitive aging when administered in people’s 40s and 50s.

(The study’s principal investigator, Dr. Lilianne R. Mujica-Parodi | Stony Brook University News)

Based on age-related destabilized brain signaling, a new study suggests a critical midlife window where metabolic interventions may stabilize brain signaling.

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Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

Longevity Prescription

Targeting NAD+ for Treating Dementia: New Harvard Op-Ed

UCI Scientists Identify New NAD+ Precursor that Counters Kidney Aging

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging