Model: 24-month-old male and female C57BL/6J mice
Dosage: 3 mg/kg/day, delivered continuously over 8 weeks

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals

Scientists show that elamipretide restores muscle and heart function in aging mice but doesn’t affect epigenetic or transcriptomic age.


Cardiovascular

Model: Male C57BL/6 mice 
Dosage: 10 mg/kg of glyburide via intragastric injections or 500 mg/kg of NMN by oral water supply daily starting at 12 months of age until death

Common Diabetes Medication Extends Life, Suggests New Study

Researchers show that glyburide, an anti-diabetes drug, extends lifespan and reduces frailty in naturally aged mice.

(The chemical structure of glyburide, a diabetes medication | PubChem)

Aging &amp; Longevity

Multi-Nation Expert Panel Agrees On Biomarkers of Aging

For the first time, a multi-nation panel of aging experts reached a consensus to designate markers of aging, which could make aging intervention testing easier.

(An aged individual holding pills and supplements meant to work against aging | UCLA)

Scientists cure type 2 diabetes by replicating the function of the pancreas with stem cells. 


Diabetes &amp; Obesity

Want to Get Fit? Look at What Sylvester Stallone Does at 78

Sylvester Stallone’s daily diet includes egg whites as well as broiled chicken and fish for plenty of protein, and his most current workouts focus on the chest, back, abs, and legs for optimal longevity.

(Even at age 78, Sylvester Stallone maintains a strikingly cut physique | YouTube)

Search Result: Frailty

Diabetes Drug Elamipretide Reverses Muscle and Heart Aging: New Study Reveals

Common Diabetes Medication Might Extend Life, Suggests New Study

Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics

2024 Research Breakthrough: Can Stem Cells Cure Diabetes?

Want to Get Fit? Look at What Sylvester Stallone Does at 78