<p>Model: 699 European adults with an average age of 63.11 years</p>


Longest Aging Clock Study to Date Shows Robust Improvement in Mortality Risk Prediction

A new study provides evidence that using aging clocks based on molecular tagging patterns on DNA (epigenetic aging clocks) to take multiple age readings across time outperforms taking single measurements in predicting mortality.

(The study’s principal investigator, Luigi Ferrucci | LinkedIn)

An Institute for Research on Aging study provides evidence that using epigenetic aging tests at multiple time points predicts mortality better than a single measurement.

Epigenetics

Top Evidence-Based Interventions to Lower Biological Age

Epigenetic aging clocks estimate biological age based on DNA molecular tagging patterns, and interventions like semaglutide and ketamine reduce these estimates in humans.

(The principal investigator behind the review on interventions that influence biological age, Dr. David Sinclair | The Society of the Four Arts)

As reviewed in this article, epigenetic aging clocks have estimated the effects of pharmaceutical interventions, lifestyle habits, supplements, and clinical interventions on biological age.

Aging &amp; Longevity

<p>Model: 20-month-old male C57BL/6 mice<br />
Dosage: 3,000 to 4,000 µg of ouabain dissolved in 27,000 to 36,000 µL of PBS injected twice per week every third week over a period of three months</p>


AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

Harvard and MIT scientists analyze decades of publicly available molecular studies with a new AI platform to uncover hundreds of previously hidden anti-aging strategies, like the drug ouabain.

A new AI platform has uncovered hundreds of pro-longevity agents based on the reanalysis of millions of mouse and human gene expression samples.

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<p data-start="97" data-end="197">Model: Aged mice (18 months old, C57BL/6 strain) and aged rhesus macaques (18–21 years old).</p>
<p data-start="97" data-end="197">Dosage: Mice received 100 µg of EVs^ABPC via tail vein injection twice per week for 4 weeks.<br data-start="297" data-end="300" data-is-only-node="" />Rhesus macaques received 200 µg/kg of EVs^ABPC intravenously once per week for 20 weeks.</p>
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Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

Eric Verdin, M.D., and Peter Attia, M.D., discuss the controversy surrounding NAD+ (nicotinamide adenine dinucleotide), the best method for replenishing NAD+, and more.


Search Result: DNA methylation

Longest Aging Clock Study to Date Shows Robust Improvement in Mortality Risk Prediction

Top Evidence-Based Interventions to Lower Biological Age

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Top Aging Expert & Peter Attia Discuss NAD+ Precursors: Taking NMN and NR Together