Model: Eight-week-old male C57BL/6J mice treated with 400 mg/kg/day of D-galactose via intraperitoneal injection for 12 weeks to induce accelerated aging.
Dosage: 400 mg/kg/day of Antarctic krill oil administered by oral gavage for 12 weeks, alongside D-galactose treatment. A comparison group received 400 mg/kg/day of fish oil under the same conditions.

Krill Oil Preserves Muscle Strength and Mitochondrial Health During Accelerated Aging

Daily krill oil supplementation preserves muscle strength, endurance, and mitochondrial health in mice with accelerated aging, outperforming fish oil.

Skin &amp; Muscle

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

University of Wisconsin researchers examine how reducing dietary protein intake may reshape nutrient sensing, metabolism, mitochondrial function, and other pathways linked to healthier aging.

(One of the leading authors on the Cell Press Blue article, Dr. Dudley Lamming | University of Wisconsin)

Researchers examine how restricting protein intake can improve metabolic health and influence aging-related pathways to extend healthspan and lifespan.

Aging &amp; Longevity

NAD+ (nicotinamide adenine dinucleotide) levels were lower among older adults with frailty—an age-related condition associated with increased vulnerability to disability, disease, and death.

Model: Chronically stressed mice 
Dosage: 9 mg/kg/day of L-serine, or 5 mg/kg/day of dasatinib combined with 50 mg/kg/day of quercetin

Supplementing chronically stressed mice with L-serine, an amino acid, counters signs of anxiety and diabetes while diverting age-promoting senescent cells within the brain’s fear center. 

Diabetes &amp; Obesity

Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The XPrize Healthspan—which will split $101 million among teams developing therapeutics to restore muscle, cognitive, and immune function in older adults—has named 10 teams receiving $1 million each.

(XPrize announced the finalists for its XPrize Healthspan competition | XPrize)

The XPrize Healthspan competition has named its top 20 finalist groups that will submit their aging intervention therapies for human trial testing.

Search Result: DNA Damage

Krill Oil Preserves Muscle Strength and Mitochondrial Health During Accelerated Aging

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

NAD+ Levels are Low Among Individuals with Frailty, New Japanese Study Shows

Cheap Supplement May Counter Stress-Induced Diabetes, Anxiety, and Brain Senescence, According to New Study

10 Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging