A new U.S. Army study shows that waist circumference and belly fat are far stronger determinants of circulating testosterone levels than aging.


An image from a previous publication authored by Dr. Karl E. Friedl, one of the U.S. Army scientists on the current study. 

Aging &amp; Longevity

Model: Young acquired niacin dependency (ANDY) mice. 
Dosage: 30 mg/kg/day of niacin

Mice engineered to have low body-wide NAD+ levels exhibit a shortened lifespan and widespread physical decline, which is largely reversed with the NAD+ booster niacin. 

Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The XPrize Healthspan—which will split $101 million among teams developing therapeutics to restore muscle, cognitive, and immune function in older adults—has named 10 teams receiving $1 million each.

(XPrize announced the finalists for its XPrize Healthspan competition | XPrize)

The XPrize Healthspan competition has named its top 20 finalist groups that will submit their aging intervention therapies for human trial testing.

The Overlooked Organ That Could Hold the Key to Fighting Aging

Scientists are researching ways to regrow the thymus, an immune organ that vanishes with age, to suppress the tolls of aging.

(The thymus [colored orange] is located in the upper chest | NAD.com)

An organ involved in immunity, the thymus, vanishes as people get older, and scientists are researching ways to regrow it to fight aging.

Immunity

Model: Old (17- to 19-month-old) C57BL6 mice 
Dosage: 14 mg/mg/day of rapamycin in food for 5 months

A purported longevity drug, rapamycin, alters immune cells associated with cancer and reduces brain inflammation in mice. 

Search Result: Bone

Why Low Testosterone Isn’t Just About Getting Older: New U.S. Army Findings Point to Belly Fat

New Mayo Clinic Study: Forcibly Depleting NAD+ Shortens Lifespan

10 Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The Overlooked Organ That Could Hold the Key to Fighting Aging

Can the Longevity Drug Rapamycin Supercharge Your Immune Cells Against Cancer?”