Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


Model: Two-month-old male C57BL/6J mice fed a high-fat diet to induce obesity 
Dosage: 400 mg/kg/day of NR for eight weeks

Scientists find that NR (nicotinamide riboside) supplementation preserves brown fat tissue in mice, reducing their body weight and maintaining the health of their mitochondria. 

An artist’s rendering of a brown fat cell (image: Alioui Ma/shutterstock.com). 

Diabetes &amp; Obesity

Multi-Nation Expert Panel Agrees On Biomarkers of Aging

For the first time, a multi-nation panel of aging experts reached a consensus to designate markers of aging, which could make aging intervention testing easier.

(An aged individual holding pills and supplements meant to work against aging | UCLA)

Participants: Physically active and healthy older adults 
Dosage: 1 gram of omega-3s (330 mg EPA plus 660 mg DHA) per day, 2,000 IU of vitamin D per day, and 30 minutes of strength training exercises three times per week

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

The “father of aging clocks” and senior study author Steve Horvath, PhD, of Harvard University (Image: quantamagazine.org). 

Search Result: Blood Pressure

Longevity Prescription

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

NAD+ Precursor NR Preserves Longevity-Promoting Brown Fat Cells, New Study Shows

Expert Panel Agrees On Biomarkers of Aging for Testing Therapeutics

Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging