Supplements like NAD+ boosters may benefit older individuals, while drugs like metformin and interventions such as physical exercise may not, according to German scientists. 

Aging &amp; Longevity

Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity. 


Brain &amp; Neurons

<p>Model: C3B6F1 hybrid mice<br />
Dosage: 42 mg/kg of rapamycin and 1.44 mg/kg of trametinib in food starting at 6 months of age</p>


Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

(The study’s lead author, Linda Partridge | The Biologist)

Combining two cancer treatment drugs, trametinib and rapamycin, extends lifespan by 29% and 27% in middle-aged female and male mice, respectively.

German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals. 

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Search Result: Autophagy

New Findings: Anti-Aging Supplements Are Not “One-Size-Fits-All”

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Longevity Secrets in Your Genome: Hidden mTOR Variants Identified

Longevity Prescription