Model: Aged mice (18 months old) underwent exploratory laparotomy under isoflurane anesthesia to induce POCD.
Dosage: Berberine was given by oral gavage at 100 mg/kg per day for 14 days after surgery.

Ancient Plant Compound Shows Promise for Protecting the Aging Brain 

Study shows berberine, a natural plant compound, protects memory in aging mice after surgery by reducing brain inflammation, stress, and cell damage.


Brain &amp; Neurons

Researchers Identify Key Cellular Changes Around Age 50 That Accelerate Aging

The Chinese Academy of Sciences' findings may explain why aging makes us sicker and suggest new ways to detect and reverse aging.

(Chinese Academy of Sciences | Ferdowsi University of Mashhad)

Aging &amp; Longevity

Participants: Healthy older adults 
Dosage: 1 mg/day of rapamycin for 8 weeks

Older adults taking low-dose rapamycin exhibit a reduction in senescent cells — cells that contribute to age-related diseases and a shorter lifespan. 

Associate professor at Oxford University and corresponding author on the study, Lynne S Cox, MA, PhD (image: researchgate.com).

Immunity

Seragon Biosciences has launched its new sleep and longevity optimizer, Enlivien, featuring technology based on a Harvard University collaboration. 


Participants: Healthy middle-aged adults (average age: 55)
Dosage: 100 mg/day of Monarda didyma L. extract, preferably at lunchtime with plenty of water, for 12 weeks

An extract made from Monarda didyma L. reduces the biological age of older adults while improving their quality of life. 

A flower from the Monarda didyma L. plant (image: nativeplanttrust.org) 

Search Result: Aged Adults

Ancient Plant Compound Shows Promise for Protecting the Aging Brain

Researchers Identify Key Cellular Changes Around Age 50 That Accelerate Aging

New Oxford Study: Powerful Longevity Drug Rapamycin Targets Cell Senescence

Enlivien: A New Dawn for Sleep and Longevity

Flower Extract Slows Cellular Aging & Improves Life Quality, New Study Shows