How to Support Muscle Function with Age: Top Evidence-Based Supplements

Data suggest certain supplements, such as L-carnitine, vitamin D, and essential minerals, support muscle function and physical performance in adults of advanced age.

Researchers from University College London review data supporting that supplements, like vitamin D, L-carnitine, and essential minerals, support muscle function during aging.

Skin &amp; Muscle

Participants: Adults over the age of 60
Dosage: 3,750 mg of niacin twice daily (after gradual dose increase), 150 mg of dihydroberberine twice daily, 50 mg of taxifolin (with 500 mg of vitamin C and 15 mg of zinc) twice daily, 50 mg of tocotrienols twice daily

A combination of supplements, including the NAD+ precursor nicotinic acid, improves cholesterol, allowing some participants to cease taking statins.  

Study conducted by Professor Emeritus Joseph Keenan, MD, at the University of Minnesota. 

Nicotinic Acid

Participants: Healthy middle-aged to older adults (average age: ~53 years)
Dosage: 1,000 mg/day of urolithin A for 28 days

Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose

A new computer simulation suggests aging occurs when cells and tissues lose their developmental goals, offering a fresh perspective on rejuvenation strategies.

(The article’s principal investigator, Michael Levin | Tufts Now)

An innovative computer model simulates aging, suggesting that cells and tissues lose their developmental goals, leading to physiological deterioration.

Search Result: Aged Adults

How to Support Muscle Function with Age: Top Evidence-Based Supplements

NAD+ Boosting Supplement Challenges Cholesterol-Lowering Statins in Anti-Aging Research

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose